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The effect of pressure on the growth of tumour cell colonies


Brú Espino, Antonio and Casero Díaz-Cano, David (2006) The effect of pressure on the growth of tumour cell colonies. Journal of theoretical biology, 243 (2). pp. 171-180. ISSN 0022-5193

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This paper describes some experiments on the manner in which external pressure affects cell colony growth in general, and tumour growth in particular. More precisely, our results show that cell colony borders growing under high-pressure conditions have geometrical and dynamical properties that are markedly different from those corresponding to growth under homeostatic, normal pressure conditions. These behaviours are characterized by means of the so-called dynamical exponents of each type of growth. These are shown to correspond to statistical properties of solutions of some stochastic partial differential equations that account for the evolution of the interface between the expanding colony and the surrounding medium.

Item Type:Article
Uncontrolled Keywords:surface-diffusion; invasive growth; solid tumors; stress; dynamics; model; interface; spheroids; stability; patterns; tumour growth; fractal properties; dynamic scaling; cell colonies
Subjects:Sciences > Mathematics > Mathematical analysis
ID Code:14862
Deposited On:18 Apr 2012 10:40
Last Modified:06 Feb 2014 10:10

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