Guria, G. T. and Herrero, Miguel A. and Zlobina, K. E. (2009) A mathematical model of blood coagulation induced by activation sources. Discrete and Continuous Dynamical Systems. Series A., 25 (1). pp. 175-194. ISSN 1078-0947
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In this work a mathematical model for blood coagulation induced by an activator source is presented. Blood coagulation is viewed as a process resulting in fibrin polymerization, which is considered as the first step towards thrombi formation. We derive and study a system for the first moments of the polymer concentrations and the activating variables. Analysis of this last model allows us to identify parameter regions which could lead to thrombi formation, both in homeostatic and pathological situations.
|Uncontrolled Keywords:||Aggregation-fragmentation equations; activator-inhibitor systems; fibrin polymerization; blood coagulation; sol-gel transition; polymerization; thrombosis; equations; kinetics; gelation; cancer; flow|
|Subjects:||Medical sciences > Medicine > Hematology|
Sciences > Mathematics > Operations research
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|Deposited On:||11 Sep 2012 07:46|
|Last Modified:||06 Feb 2014 10:39|
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