Universidad Complutense de Madrid
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Coexistence of mcr-1 and blaNDM-1 in Escherichia coli from Venezuela

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Delgado Blas, José Francisco y Martínez Ovejero, Cristina y Abadia Patiño, Lorena y González Zorn, Bruno (2016) Coexistence of mcr-1 and blaNDM-1 in Escherichia coli from Venezuela. Antimicrobial agents and chemotherapy, 60 (10). pp. 6356-8. ISSN 0066-4804

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URL Oficial: http://aac.asm.org/content/60/10/6356.long



Resumen

We studied the presence of the mobile colistin resistance gene mcr-1 in human, animal, and environmental Enterobacteriaceae samples from Cumana, Venezuela, that were collected in 2015. The mcr-1 gene was detected in 2/93 Escherichia coli isolates from swine (novel ST452) and human (ST19) samples that were resistant to colistin. Whole-genome sequencing and transformation experiments identified mcr-1 on an IncI2 plasmid. One of the isolates also bore the widely spread carbapenemase NDM-1. A One Health approach is necessary to further elucidate the flux of these high-risk genes.


Tipo de documento:Artículo
Materias:Ciencias Biomédicas > Veterinaria
Código ID:39608
Depositado:09 Ene 2017 16:22
Última Modificación:09 Ene 2017 16:22

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