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Antibiotic-resistant Klebsiella pneumoniae and Escherichia coli high-risk clones and an IncFII(k) mosaic plasmid hosting Tn1 (blaTEM-4) in isolates from 1990 to 2004

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Rodríguez, Irene y Novais, Ângela y Lira, Felipe y Valverde, Aránzazu y Curião, Tânia y Martínez, José Luis y Baquero, Fernando y Cantón, Rafael y Coque, Teresa M (2015) Antibiotic-resistant Klebsiella pneumoniae and Escherichia coli high-risk clones and an IncFII(k) mosaic plasmid hosting Tn1 (blaTEM-4) in isolates from 1990 to 2004. Antimicrobial agents and chemotherapy, 59 (5). pp. 2904-8. ISSN 1098-6596

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URL Oficial: http://aac.asm.org/content/59/5/2904



Resumen

We describe the genetic background of bla(TEM-4) and the complete sequence of pRYC11::bla(TEM-4), a mosaic plasmid that is highly similar to pKpQIL-like variants, predominant among TEM-4 producers in a Spanish hospital (1990 to 2004), which belong to Klebsiella pneumoniae and Escherichia coli high-risk clones responsible for the current spread of different antibiotic resistance genes. Predominant populations of plasmids and host adapted clonal lineages seem to have greatly contributed to the spread of resistance to extended-spectrum cephalosporins.


Tipo de documento:Artículo
Materias:Ciencias Biomédicas > Veterinaria
Código ID:39627
Depositado:09 Ene 2017 16:31
Última Modificación:09 Ene 2017 16:31

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