Universidad Complutense de Madrid
E-Prints Complutense

First molecular detection and characterization of herpesvirus and poxvirus in a Pacific walrus (Odobenus rosmarus divergens)

Impacto

Descargas

Último año



Melero Asensio, Mar y García Párraga, Daniel y Corpa, Juan Manuel y Ortega, Joaquín y Rubio Guerri, Consuelo y Crespo, José Luis y Rivera Arroyo, Belén y Sánchez-Vizcaíno, José Manuel (2014) First molecular detection and characterization of herpesvirus and poxvirus in a Pacific walrus (Odobenus rosmarus divergens). BMC veterinary research, 10 . p. 968. ISSN 1746-6148

[img]
Vista previa
PDF
Creative Commons License
Esta obra está bajo una licencia de Creative Commons: Reconocimiento.

1MB

URL Oficial: http://bmcvetres.biomedcentral.com/articles/10.1186/s12917-014-0308-2



Resumen

BACKGROUND

Herpesvirus and poxvirus can infect a wide range of species: herpesvirus genetic material has been detected and amplified in five species of the superfamily Pinnipedia; poxvirus genetic material, in eight species of Pinnipedia. To date, however, genetic material of these viruses has not been detected in walrus (Odobenus rosmarus), another marine mammal of the Pinnipedia clade, even though anti-herpesvirus antibodies have been detected in these animals.

CASE PRESENTATION

In February 2013, a 9-year-old healthy captive female Pacific walrus died unexpectedly at L'Oceanografic (Valencia, Spain). Herpesvirus was detected in pharyngeal tonsil tissue by PCR. Phylogenetic analysis revealed that the virus belongs to the subfamily Gammaherpesvirinae. Poxvirus was also detected by PCR in skin, pre-scapular and tracheobronchial lymph nodes and tonsils. Gross lesions were not detected in any tissue, but histopathological analyses of pharyngeal tonsils and lymph nodes revealed remarkable lymphoid depletion and lymphocytolysis. Similar histopathological lesions have been previously described in bovine calves infected with an alphaherpesvirus, and in northern elephant seals infected with a gammaherpesvirus that is closely related to the herpesvirus found in this case. Intracytoplasmic eosinophilic inclusion bodies, consistent with poxviral infection, were also observed in the epithelium of the tonsilar mucosa.

CONCLUSION

To our knowledge, this is the first molecular identification of herpesvirus and poxvirus in a walrus. Neither virus was likely to have contributed directly to the death of our animal.


Tipo de documento:Artículo
Palabras clave:Herpesvirus, Poxvirus, Walrus, Pinniped
Materias:Ciencias Biomédicas > Veterinaria
Código ID:39631
Depositado:20 Dic 2016 09:32
Última Modificación:22 Dic 2016 11:49

Descargas en el último año

Sólo personal del repositorio: página de control del artículo