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EPIMHC: a curated database of MHC-binding peptides for customized computational vaccinology

Reche, Pedro A and Zhang, Hong and Glutting, John-Paul and Reinherz, Ellis L (2005) EPIMHC: a curated database of MHC-binding peptides for customized computational vaccinology. Bioinformatics (Oxford, England), 21 (9). pp. 2140-1. ISSN 1367-4803

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Abstract

SUMMARY: EPIMHC is a relational database of MHC-binding peptides and T cell epitopes that are observed in real proteins. Currently, the database contains 4867 distinct peptide sequences from various sources, including 84 tumor-associated antigens. The EPIMHC database is accessible through a web server that has been designed to facilitate research in computational vaccinology. Importantly, peptides resulting from a query can be selected to derive specific motif-matrices. Subsequently, these motif-matrices can be used in combination with a dynamic algorithm for predicting MHC-binding peptides from user-provided protein queries. AVAILABILITY: The EPIMHC database server is hosted by the Dana-Farber Cancer Institute at the site http://immunax.dfci.harvard.edu/bioinformatics/epimhc/

Item Type:Article
Subjects:Medical sciences > Medicine > Immunology
Medical sciences > Biology > Molecular biology
Sciences > Computer science > Bioinformatics
ID Code:9332
Deposited On:06 Aug 2009 09:48
Last Modified:06 Feb 2014 08:23

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