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EPIMHC: a curated database of MHC-binding peptides for customized computational vaccinology



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Reche, Pedro A y Zhang, Hong y Glutting, John-Paul y Reinherz, Ellis L (2005) EPIMHC: a curated database of MHC-binding peptides for customized computational vaccinology. Bioinformatics (Oxford, England), 21 (9). pp. 2140-2141. ISSN 1367-4803

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URL Oficial: http://bioinformatics.oxfordjournals.org/content/21/9/2140.abstract


EPIMHC is a relational database of MHC-binding peptides and T cell epitopes that are observed in real proteins. Currently, the database contains 4867 distinct peptide sequences from various sources, including 84 tumor-associated antigens. The EPIMHC database is accessible through a web server that has been designed to facilitate research in computational vaccinology. Importantly, peptides resulting from a query can be selected to derive specific motif-matrices. Subsequently, these motif-matrices can be used in combination with a dynamic algorithm for predicting MHC-binding peptides from user-provided protein queries. AVAILABILITY: The EPIMHC database server is hosted by the Dana-Farber Cancer Institute at the site http://immunax.dfci.harvard.edu/bioinformatics/epimhc/

Tipo de documento:Artículo
Materias:Ciencias Biomédicas > Medicina > Inmunología
Ciencias Biomédicas > Biología > Biología molecular
Ciencias > Informática > Bioinformática
Código ID:9332
Depositado:06 Aug 2009 09:48
Última Modificación:06 Oct 2014 10:33

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