Reche, Pedro A and Zhang, Hong and Glutting, John-Paul and Reinherz, Ellis L (2005) EPIMHC: a curated database of MHC-binding peptides for customized computational vaccinology. Bioinformatics (Oxford, England), 21 (9). pp. 2140-1. ISSN 1367-4803
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Abstract
SUMMARY: EPIMHC is a relational database of MHC-binding peptides and T cell epitopes that are observed in real proteins. Currently, the database contains 4867 distinct peptide sequences from various sources, including 84 tumor-associated antigens. The EPIMHC database is accessible through a web server that has been designed to facilitate research in computational vaccinology. Importantly, peptides resulting from a query can be selected to derive specific motif-matrices. Subsequently, these motif-matrices can be used in combination with a dynamic algorithm for predicting MHC-binding peptides from user-provided protein queries. AVAILABILITY: The EPIMHC database server is hosted by the Dana-Farber Cancer Institute at the site http://immunax.dfci.harvard.edu/bioinformatics/epimhc/
| Item Type: | Article |
|---|---|
| Subjects: | Medical sciences > Medicine > Immunology Medical sciences > Biology > Molecular biology Sciences > Computer science > Bioinformatics |
| ID Code: | 9332 |
| Deposited On: | 06 Aug 2009 11:48 |
| Last Modified: | 30 Sep 2009 12:46 |
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