Publication: Efectos clínicos y antiinflamatorios de la radiación láser de Nd:YAG aplicada adiionalmente al tratamiento no-quirúrgico en periodontitis crónica
Loading...
Official URL
Full text at PDC
Publication Date
2012
Authors
Advisors (or tutors)
Editors
Journal Title
Journal ISSN
Volume Title
Publisher
Citations
Exportar
Abstract
El objetivo principal del presente trabajo de investigación fue comparar la respuesta entre el tratamiento periodontal convencional y el mismo tratamiento complementado con Terapia Láser, mediante el empleo de la radiación procedente de un láse de Nd:YAG, bien aplicada en una única dosis o bien en dosis repetidas desde un punto de vista clínico, inflamatorio y antioxidante, en pacientes adultos afectados de periodontitis crónica.En términos generales se observó a nivel clínico una mejora de la enfermedad periodontal para los tres grupos de estudio.No se observaron complicaciones durante el periodo de seguimiento tales como abcesos o infecciones, tolerándose de forma positiva los 3 tratamientos por parte de los pacientes.
[ABSTRACT] The main purpose of this work was to compare the reaction between the conventional periodontal treatment and the same treatment completed with Laser Therapy, specifically with the radiation of the laser Nd:YAG, in one or several dosis, in adult patients suffering from chronic periodontitis. In general terms, we observed an improvement of the periodontal disease in a clinical level of the three groups of this study. We have not observed complications during the follow-up period such as infections or abscesses, and the treatments were tolerated positively by the patients.
Description
UCM subjects
Unesco subjects
Keywords
Citation
1. AAP (The American Academy of Periodontology). The Research, Science and Therapy Committee of the Ameri- can Academy of Periodontology, Cohen RE, Ammons WF. Revised by Rossman JA. Lasers in periodontics (Academy report). J Periodontol 2002; 73: 1231–1239.
2. Abbas AK, Litchtman AH, Pober JS. Cellular and molecular immunology 1999; chapter 3. W.B. Saunders.
3. Adriaens PA, Edwards CA, De Boever JA, Loesche WJ. Ultrastructural observations on bacterial invasion in cementum and radicular dentin of periodontally diseased human teeth. J Periodontol 1988; 59: 493–503.
4. Ainamo J, Bay I. Problems and proposals for recording gingivitis and plaque. Int Dent J 1975; 25: 229-235.
5. Amin A, Dave M, Attur M, Abramson S. COX-2, NO and cartilage damage and repair. Curr Rheumatol Rep 2000, 2: 447-453.
6. Aoki A, Sasaki KM, Watanabe H, Ishiwaka I. Lasers in non surgical periodontal therapy. Periodontol 2000 2004; 36: 59-97.
7. Armitage GC. Development of a Classification System for Periodontal Diseases and Conditions. Ann Periodontol 1999; 4(1):1-6. Review.
8. Assuma R, Oates T, Cochran C, Amar S, Graves DT. IL-1 and TNF antagonists inhibit the inflammatory response and bone loss in experimental periodontitis. J Immunol 1998; 160: 403–409.
9. Bader HI. Use of laser in periodontic. Dent Clin North Am 2000; 44: 779-91.
10. Batista AC, Silva TA, Chun JH, Lara VS. Nitric oxide synthesis and severity of human periodontal disease.Oral Dis 2002; 8(5): 254-60.
11. Ben Hatit Y, Blum R, Severin C, Maquin M, Jabro MH. The effects of a pulsed Nd:YAG laser on subgingival bacterial flora and on cementum: an in vivo study. J Clin Laser Med Surg 1996; 14: 137–143.
12. Bertolini DR, Nedwin GE, Bringman TS, Smith DD, Mundy GR. Stimulation of bone resorption and inhibition of bone formation in vitro by human tumor necrosis factors. Nature 1986; 319: 516-518.
13. Billingham ME. Cytokines as inflammatory mediators. British Medical Bulletin 1987; 43: 350-357.
14. Brock GR, Butterworth CJ, Matthews JB, Chapple IL. Local and systemic total antioxidant capacity in periodontitis and health. J Clin Periodontol 2004; 31(7): 515-521.
15. Buchanan SA, Robertson PB. Calculus removal by scaling/root planing with and without surgical access. J Periodontol 1987; 58: 159–163.
16. Chapple IL, Brock GR, Milward MR, Ling N, Matthews JB. Compromised GCF total antioxidant capacity in periodontitis: cause or effect? J Clin Periodontol 2007; 34(2): 103-110.
17. Chapple IL, Landini G, Griffiths GS, Patel NC, Ward RS. Calibration of the Periotron 8000 and 6000 by polynomial regression. J Periodontal Res 1999; 34(2):79-86.
18. Chapple IL. Reactive oxygen species and antioxidants in inflammatory diseases. J Clin Periodontol 1997; 24(5): 287-96.
19. Claffey N, Nylund K, Kiger R, Garrett S, Egelberg J. Diagnostic predictability of scores of plaque, bleeding, suppuration, and probing pocket depths for probing attachment loss. 31⁄2 years of observation following initial therapy. J Periodontol 1990; 17: 108–114.
20. Cobb CM, Low SB, Coluzzi DJ. Lasers and the treatment of chronic periodontitis. Dent Clin North Am 2010;54:35-53.
21. Cobb CM, McCawley TK, Killoy WJ. A preliminary study on the effects of the Nd:YAG laser on root surfaces and sub- gingival microflora in vivo. J Periodontol 1992; 63: 701– 707.
22. Cochran D. Inflammation and bone loss in periodontal disease. J Periodontol 2008; Suppl 79: 1569-1576.
23. Costerton JW, Cheng KJ, Geesey GG, Ladd TI, Nickel JC, Dasgupta M et al. Bacterial biofilms in nature and disease. Annu Rev Microbiol 1987; 41: 435-64.
24. Costerton JW, Donlan RM. Biofilms: Survival Mechanisms of Clinically Relevant Microorganisms. Clin Microbiol Rev 2002; 15(2):167-93. Review.
25. de Andrade AK, Feist IS, Pannuti CM, Cai S, Zezell DM, De Micheli G. Nd:YAG laser clinical assisted in Class II furcation treatment. Lasers Med Sci 2008; 23:341-347.
26. Delaleu N, Bickel M. Interleukin-1 beta and interleukin-18: regulation and activity in local inflammation. Periodontol 2000 2004; 35:42–52.
27. Deli a AJ, Oates T, Assuma R, Schwartz Z, Cochran D, Amar S, Graves DT. Soluble antagonists to interleukin-1 (IL-1) and tumor necrois factor (TNF) inhibits loss of tissue attachment in experimental periodontitis. J Clin Periodontol 2001; 28: 233–240.
28. Dinarello C. Biologic basis for interleukin-1 in disease. Blood 1996; 87: 2095-2147.
29. Eltas A, Orbak R. Effect of 1,064-nm Nd:YAG laser therapy on GCF IL-1à and MMP-8 levels in patients with chronic periodontitis Lasers Med Sci 2012; 27(3):543-50.
30. Geusic JE, Marcos HM, Van Uitert LG. Laser oscillations in Nd-doped yttrium aluminum, yttrium gallium, and gadolinium garnets. Appl Phys Lett 1964; 4:182.
31. Giannelli M, Bani D, Viti C, Tani A, Lorenzini L, Zecchi-Orlandini S, Formigli L. Comparative evaluation of the effects of different photoablative laser irradiation protocols on the gingiva of periodontopathic patients. Photomed Laser Surg 2012; 30(4):222-30.
32. Goldman L, Hornby P, Meyer R, Goldman B. Impact of the laser on dental caries. Nature 1964; 203:417.
33. Gómez C, Bisheimer M, Costela A, García-Moreno I., García A, García J.A. Evaluation of the effects of Er:YAG and Nd:YAG lasers and ultrasonic instrumentation on root surfaces. Photomedicine and Laser Surgery 2009 Feb; 27: 43-48.
34. Gómez C, Domínguez A, García-Kass AI, García-Nuñez JA. Adjunctive Nd:YAG laser application in chronic periodontitis: clinical, immunological, and microbiological aspects. Lasers Med Sci 2011 26:453–463.
35. Gowen M, Mundy GR. Actions of recombinant IL-α and interferon-α on bone resorption in vitro. Journal of Immunology 1986; 136: 2478-2482.
36. Graves D, Cochran D. The contribution of IL 1 and TNF to periodontal tissue destruction. J Periodontol 2003; 74: 391-401.
37. Graves D, Oskoui M, Volejnikova S, et al. Tumor necrosis factor modulates fibroblast apoptosis, PMN recruitment, and osteoclast formation in response to P. gingivalis infection. J Dent Res 2001; 80: 1875-1879
38. Graves DT, Delima AJ, Assuma R, Amar S, Oates T, Cochran D. Interleukin-1 and tumor necrosis factor antagonists inhibit the progression of inflammatory cell infiltration toward alveolar bone in experimental perio- dontitis. J Periodontol 1998; 69: 1419–1425.
39. Hock J, Krishnan V, Onyia J, Bidwell J, Milas J, Stanislaus D. Osteoblast apoptosis and bone turnover. J Bone Miner Res 2001; 16: 975-984.
40. Ishikawa I, Aoki A, Takasaki AA. Potential applications of Erbium: YAG laser in periodontics. J Periodontal Res 2004; 39(4): 275-285. Review.
41. Jiang Y, Magli L, Russo M. Bacterium-dependent induction of cytokines in mononuclear cells and their pathologic consequences in vivo. Infect Immun 1999; 67: 2125–2130.
42. Kaldahl WB, Kalkwarf KL, Patil KD. A review of longitudinal studies that compared periodontal therapies. J Periodontol. 1993 Apr; 64(4): 243-53.
43. Kara C, Demir T, Orbak R, Tezel A. Effect of Nd:YAG laser irradiation on the treatment of oral malodour associated with chronic periodontitis. Int Dent J 2008; 58:151-158.
44. Karlsson MR, Diogo Löfgren CI, Jansson HM. The effect of laser therapy as an adjunct to non-surgical periodontal treatment in subjects with chronic periodontitis: A systematic review. J Periodontol 2008; 79: 2021-2028.
45. Kranendonk, A. A., Van der Reijden, W. A., Van Winkelhoff, A. J. & Van der Weijden, G. A. (2010) The bactericidal effect of a Geniuss Nd:YAG laser. International Journal of Dental Hygiene 8, 63–67.
46. Lam J, Takeshita S, Barker JE, Kanagawa O, Ross FP, Teitelbaum SL. TNF-alpha induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand. J Clin Invest 2000; 12: 1481-1488.
47. Listgarten MA, Ellegaard B. Electron microscopic evidence of a cellular attachment between junctional epithelium and dental calculus. J Periodontal Res 1973; 8: 143-150.
48. Liu CM, Hou LT, Wong MY, Lan WH. Comparison of Nd:YAG laser versus scaling and root planing in peri- odontal therapy. J Periodontol 1999;70:1276-1282.
49. Liu YC, Lerner UH, Teng YT. Cytokine responses against periodontal infection: protective and destructive roles. Periodontol 2000 2010; 52(1):163-206.
50. Marsh PD. Dental plaque: biological significance of a biofilm and community life-style. J Clin Periodontol 2005; 32 Suppl 6:7-15. Review.
51. Meikle MC, Atkinson SJ, Ward RV, Murphy J, Reynolds JJ. Gingival fibroblasts degrade type 1 collagen films when stimulated with tumor necrosis factor and IL-1 evidence that breakdown is mediated by metalloproteinase. J Periodontal Res 1989; 24: 207-213.
52. Miserendino LJ, Levy GC, Abt E, Rizoiu IM. Histologic effects of a thermally cooled Nd:YAG laser on the dental pulp and supporting structures of rabbit teeth. Oral Surgery Oral Medicine Oral Pathology 1994; 78: 93-100.
53. Miserendino LJ, Neiburger EJ, Pick RM. Current status of lasers in dentistry. Ill Dent J 1987; 56:254
54. Miyazaki A, Yamaguchi T, Nishikata J y cols. Effects of Nd: YAG and CO2 laser treatment and ultrasonic scaling on periodontal pockets of chronic periodontitis patients. J Periodontol 2003; 74: 175-80.
55. Nakashima T, Kobayashi Y, Yamasaki S, et al. Protein expression and functional difference of membrane- bound and soluble receptor activator of NF-kappaB ligand: Modulation of the expression by osteotropic factors and cytokines. Biochem Biophys Res Commun 2000; 275:768-775.
56. Neill ME, Mellonig JT. Clinical efficacy of the Nd:YAG laser for combination periodontitis therapy. Pract Peri- odontics Aesthet Dent 1997; 9(Suppl. 6):1-5.
57. Niemz MH. Laser–tissue Interaction. Fundamentals and Applications. Berlin: Springer-Verlag, 1996: 64–65.-257.
58. Noguchi T, Sanaoka A, Fukuda M, Suzuki S, Aoki T. Combined effects of Nd:YAG laser irradiation with local antibiotic application into periodontal pockets. J Int Acad Periodontol 2005; 7:8-15.
59. Offenbacher S. Periodontal diseases: Pathogenesis. Ann Periodontol 1996; 1: 821-878.
60. Page RC, Kornman KS. The pathogenesis of human periodontitis: An introduction. Periodontol 2000 1997; 14:9-11.
61. Perry DA, Goodis HE, White JM. In vitro study of the effects of Nd:YAG laser probe parameters on bovine oral soft tissue excision. Lasers Surg Med 1997; 20(1): 39-46.
62. Pfize maier K, Wajant H, Grell M. Tumor necrosis factors in 1996. Cytokine Growth Factor Rev 1996; 7: 271-277.
63. Pick RM, Colvard MD. Current status of lasers in soft tissue dental surgery. J Periodontol 1993; 64:589-602.
64. Polson AM, Frederic GT, Ladenheim S, Hanes PJ. The production of a root surface smear layer by instrumenta- tion and its removal by citric acid. J Periodontol 1984; 55: 443–446.
65. Qadri T, Javed F, Poddani P, Tunér J, Gustafsson A. Long-term effects of a single application of a water-cooled pulsed Nd:YAG laser in supplement to scaling and root planing in patients with periodontal inflammation. Lasers Med Sci 2011; 26:763–766.
66. Qadri T, Poddani P, Javed F, Tuner J, Gustafsson A. A short-term evaluation of Nd:YAG laser as an adjunct to scaling and root planing in the treatment of periodon- tal inflammation. J Periodontol 2010;81:1161-1166.
67. Qadri, T, Miranda L, Tuner J, Gustafsson A. The short-term effects of low-level lasers as adjunct therapy in the treatment of periodontal inflammation. J Clin Periodontol 2005; 32: 714–719.
68. Radvar M, MacFarlane TW, MacKenzie D, Whitters CJ, Payne AP, Kinane DF. An evaluation of the Nd:YAG laser in periodontal pocket therapy. Br Dent J 1996; 180:57-62.
69. Renvert S, Wikstrom M, Dahlen G, Slots J, Egelberg J. Effect of root debridement on the elimination of Actinobacillus actinomycetemcomitans and Bacteroides gingivalis from periodontal pockets. J Clin Periodontol 1990; 17: 345–350.
70. Rodan G, Martin T. Therapeutic approaches to bone diseases. Science 200; 289: 1508-1514.
71. Romanos GE. Clinical applications of the Nd:YAG laser in oral soft tissue surgery and periodontology. J Clin Laser Med Surg 1994; 12(2): 103-108.
72. Sanz M, Teughels W, Group A of European Workshop on Periodontology. Innovations in non-surgical peri- odontal therapy: Consensus Report of the Sixth Euro- pean Workshop on Periodontology. J Clin Periodontol 2008; 35(8 Suppl.):3-7.
73. Sbordone L, Ramaglia L, Gulletta E, Iacono V. Recolonization of the subgingival microflora after scaling and root planing in human periodontitis. J Periodontol 1990; 61(9): 579-84.
74. Schoop U, Moritz A, Kluger W, Patruta S, Goharkhay K, Sperr W, Wernisch J, Gattringer R, Mrass P, Georgopoulos A. The Er: YAG laser in endodontics: results of an in vitro study. Lasers Surg Med 2002; 30(5): 360-364.
75. Schroeder HE. Formation and inhibition of dental calculus. Berne: Hans Huber Publishers 1969.
76. Schwarz F, Aoki A, Sculean A, Georg T, Scherbaum W, Becker J. In vivo effects of an Er:YAG laser, an ultrasonic system and scaling and root planing on the biocompati- bility of periodontally diseased root surfaces in cultures of human PDL fibroblasts. Lasers Surg Med 2003; 33: 140–147.
77. Schwarz F, Putz N, Georg T, Reich E. Effect of an Er:YAG laser on periodontally involved root surfaces: an in vivo and in vitro SEM comparison. Lasers Surg Med 2001; 29: 328–335.
78. Sgolastra F, Petrucci A, Gatto R, Marzo G, Monaco A. Photodynamic therapy in the treatment of chronic periodontitis: a systematic review and meta-analysis. Lasers Med Sci; 2011 Oct 16.
79. Shirodaria S, Smith J, McKay IJ, Kennett CN, Hughes FJ. Polymorphisms in the IL-1A gene are correlated with levels of interleukin-1 alpha protein in gingival crevicular fluid of teeth with severe periodontal disease. J Dent Res 2000; 79: 1864-1869.
80. Sjöström L, Friskopp J. Laser treatment as an adjunct to debridement of periodontal pockets. Swed Dent J 2002; 26:51-57.
81. Slot DE, Kranendonk AA, Paraskevas S, Van der Weijden F. The effect of a pulsed Nd:YAG laser in non-surgical periodontal therapy. Systematic Review. J Periodontol 2009; 80:1041-1056.
82. Snitzer E. Optical laser action of Nd in barium crown glass. Phys Rev Lett 1961; 7:444-446.
83. Stashenko P, Dewhirst F, Peros W, Kent RL, Ago J. Synergistic interactions between interleukin 1, tumor necrosis factor, and lymphotoxin in bone resorption. J Immunol 1987; 138: 1464-1468.
84. Stashenko P, Fujiyoshi P, Obernesser MS, Prostak L, Haffajee AD, Socransky SS. Levels of interleukin 1 beta in tissue from sites of active periodontal state. J Clin Periodontol 1991; 18: 548-554.
85. Stern RH, Sognnaes RF. Laser inhibition of dental caries suggested by first tests in vivo. J Am Dent Assoc 1972; 85:1087-1090.
86. Sulewski JG. Historical survey of laser dentistry. Dent Clin North Am 2000; 44: 717–752.
87. Takatis DN, Schneerberger G, Dziak, R. Recombinant interleukin-1 stimulates prostraglandin E2 production by osteoblastic cells: synergy with parathyroid hormone. Calcified Tissue International 1988; 42: 358-362.
88. Theilade J. Electron microscopic study of calculus attachment to smooth surfaces. Acta Odontologica Scandinavia 1964; 22: 379-387.
89. Tsai CC, Chen HS, Chen SL, Ho YP, Ho KY, Wu YM, Hung CC. Lipid peroxidation: a possible role in the induction and progression of chronic periodontitis. J Periodontal Res 2005; 40(5): 378-384.
90. Waerhaug J. Healing of the dentoepithelial junction following subgingival plaque control. II. As observed on extracted teeth. J Periodontol 1978; 49: 119–134.
91. Waerhaug J. The gingival pocket. Odontologisk Tidskrift 1952; 60 Suppl 1.
92. Watanabe H, Ishikawa I, Suzuki M, Hasegawa K. Clinical assessments of the erbium:YAG laser for soft tissue surgeryand scaling. J Clin Laser Med Surg 1996; 14: 67–75.
93. Waterman WH, Sha'afi RI. A mitogen-activated protein kinase independent pathway involved in the phosphorylation and activation of cytosolic phospholipase A2 in human neutrophils stimulated with tumor necrosis factor-alpha. Biochem Biophys Res Commun 1995; 209(1): 271-8.
94. White JM, Goodis HE, Rose CL. Use of the pulsed Nd:YAG laser for intraoral soft tissue surgery. Lasers Surg Med 1991; 11: 455–461.
95. Winkel EG, van Winkelhoff AJ, Timmerman, MF, Vangsted T, van der Velden U. Effects of metronidazole in patients with ‘‘refractory’’ periodontitis associated with Bacteroides forsythus. J Clin Periodontol 1997; 24: 573–579.
96. Zander HA, Hazen SP, Scott DB. Mineralization of dental calculus. Proceedings of the Society of Experimental Biology and Medicine 1960; 103: 257-260.