Universidad Complutense de Madrid
E-Prints Complutense

The microbiome as a human organ

Impacto

Downloads

Downloads per month over past year



Baquero, Fernando and Nombela, César (2012) The microbiome as a human organ. Clinical Microbiol Infect, 18 . pp. 2-4.

[img]
Preview
PDF
192kB

Official URL: http://onlinelibrary.wiley.com/doi/10.1111/j.1469-0691.2012.03916.x/abstract



Abstract

The human organism is a complex structure composed of cells belonging to all three domains of life on Earth, Eukarya, Bacteria and Archaea, as well as their viruses. Bacterial cells of more than a thousand taxonomic units are condensed in a particular functional collective domain, the intestinal microbiome. The microbiome constitutes the last human organ under active research. Like other organs, and despite its intrinsic complexity, the microbiome is readily inherited, in a process probably involving ‘small world’ power law dynamics of construction in newborns. Like any other organ, the microbiome has physiology and pathology, and the individual (and collective?) health might be damaged when its collective population structure is altered. The diagnostic of microbiomic diseases involves metagenomic studies. The therapeutics of microbiome-induced pathology include microbiota transplantation, a technique increasingly available.


Item Type:Article
Uncontrolled Keywords:Human organ, Microbiomology, Transplatation
Subjects:Medical sciences > Medicine > Medical genetics
Medical sciences > Biology > Microbiology
ID Code:21704
Deposited On:14 Jun 2013 10:27
Last Modified:25 May 2015 10:35

Origin of downloads

Repository Staff Only: item control page