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A simple experimental set-up for the determination of the complex dielectric permittivity of biological tissues at microwave frequencies

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2004
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Horizon House Publications Ltd
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In this paper a simple experimental set-up is presented to determine the complex dielectric permittivity of biological tissues at the industrial frequency of 2.45 GHz. For this purpose, the scattering parameters of biological samples, which are placed in a sample holder inside a waveguide, are measured and compared with those obtained from numerical analysis of the sample using a FE technique with an adaptive mesh. Systematic errors are minimized by a precise calibration of the experimental system. The results obtained are in very good agreement with well-known published data. The simplicity of the experimental set-up makes this technique a very practical tool for detecting and quantifying changes in the complex dielectric permittivity of organs poisoned with heavy metal pollutants.
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European Microwave Conference (EuMC) (34.2004.Amsterdam, Holanda). © IOP Publishing Ltd. This work has been sponsored by the Ministerio de Ciencia y Tecnología, project FIT-070000-2002-135.
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1) Becache, E., Joly, P., 2001, On the analysis of Berenger’s perfectly matched layers for Maxwell equations INRIA, Report No 4164. 2) Fricke, H., 1925, The electric capacity of suspensions with special reference to blood, J. Gen. Physiol., 9, 137–52. 3) Fuhr, G., Zimmermann, U., Shirley, S.G., 1996, Cell Motion in Time Varying Fields: Principles and Potential in Electromanipulation of Cells, ed. U. Zimmermann, G.A. Neil (Boca Raton, FL: CRC Press) pp 259–328. 4) Gabriel, S., Lau, R.W., Gabriel, C., 1996, The dielectric properties of biological tissues: III. Parametric models for the dielectric spectrum of tissues, Phys. Med. Biol., 41, 2271–93. 5) Gimsa, J., Wachner, D., 2001, Analytical description of the transmembrane voltage induced on arbitrarily oriented ellipsoidal and cylindrical cells, Biophys. J., 81, 1888–96. 6) Huang, J.P., Yu, K.W., 2002, Dielectric behaviour of oblate spheroidal particles: application to erythrocytes suspensions, Commun. Theor. Phys., 1, 82–7. 7) Jin, J., 1993, The Finite Element Method in Electromagnetics (New York: Wiley). 8) Liu, L.M., Cleary, S.F., 1995, Absorbed energy distribution from radiofrequency electromagnetic radiation in mammalian cell model: effect of membrane-bound water, Bioelectromagnetics, 16, 160–71. 9) Miller, R.D., Jones, T.B., 1993, Electro orientation of ellipsoidal erythrocytes, Biophys. J., 64, 1588–95. 10) Morse, P.M., Feshbach, H., 1953, Methods of Theoretical Physics (New York: McGraw-Hill). 11) Sebastián, J.L., Muñoz, S., Sancho, M., Miranda, J.M., 2001, Analysis of the influence of the cell geometry orientation and cell proximity effects on the electric field distribution from direct RF exposure, Phys. Med. Biol., 46, 213–25. 12) Thuery, J., 1992, Microwaves: Industrial, Scientific and Medical Applications, ed. Edward, H. Grant (Artech House).