Publication: Desarrollo embriológico de la glándula submandibular
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2016-04-18
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Universidad Complutense de Madrid
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Abstract
Numerosos autores han analizado el desarrollo de la glándula submandibular desde diferentes perspectivas. Estos análisis señalan su origen, en humanos, a partir de una proliferación del epitelio del suelo de la boca a nivel del surco paralingual medial, entre la 6º-7º semana. El engrosamiento epitelial se invagina en el mensénquima subyacente. Tras esta fase se produce un crecimiento hasta formar ramificaciones distales y aparece luz en los conductos. El desarrollo en roedores se inicia en embriones de 11.5 días en ratón; y 14 días en rata. Durante el desarrollo se suceden acontecimientos similares al desarrollo en humanos. Investigaciones recientes se han centrado en el papel de la inervación parasimpática en el desarrollo de la glándula submandibular...
Submandibular salivary gland is a tubuloacinosa gland that is mixed in humans. Therefore, it can also be called seromucous. This gland occupies the side of the suprahyoid region between the mandible and mylohyoid muscle. From a macroscopic point of view, the excretory duct (Wharton) starts from the sublingual extension of the gland and finishes at the sublingual caruncula, located on either side of the lingual frenulum. The hypoglossal nerve, together with the lingual veins, is related to the deep surface of the gland. The lingual nerve and parasympathetic ganglia are related to the excretory duct of the gland. Many authors have analyzed the development of the submandibular gland from different perspectives. These analyses indicate the origin of the gland, in humans, from a proliferation of the epithelium of the mouth floor at the paralingual medial groove level. Most of them describe the emergence of the outline between the 6th-7th week of development, but with differences in the size of the embryo. The epithelial thickening invaginates in the underlying mesenchyme and initially forms a solid cord. After this phase of invagination, growth occurs to form distal branches that will result in the secretory acini of the gland .Finally, during morphogenesis of the gland begins to appear light in the ducts. The condensed mesenchyme surrounding the epithelium, will result in the capsule and stroma of the gland...
Submandibular salivary gland is a tubuloacinosa gland that is mixed in humans. Therefore, it can also be called seromucous. This gland occupies the side of the suprahyoid region between the mandible and mylohyoid muscle. From a macroscopic point of view, the excretory duct (Wharton) starts from the sublingual extension of the gland and finishes at the sublingual caruncula, located on either side of the lingual frenulum. The hypoglossal nerve, together with the lingual veins, is related to the deep surface of the gland. The lingual nerve and parasympathetic ganglia are related to the excretory duct of the gland. Many authors have analyzed the development of the submandibular gland from different perspectives. These analyses indicate the origin of the gland, in humans, from a proliferation of the epithelium of the mouth floor at the paralingual medial groove level. Most of them describe the emergence of the outline between the 6th-7th week of development, but with differences in the size of the embryo. The epithelial thickening invaginates in the underlying mesenchyme and initially forms a solid cord. After this phase of invagination, growth occurs to form distal branches that will result in the secretory acini of the gland .Finally, during morphogenesis of the gland begins to appear light in the ducts. The condensed mesenchyme surrounding the epithelium, will result in the capsule and stroma of the gland...
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Tesis inédita de la Universidad Complutense de Madrid de la Facultad de Odontología del Departamento de Anatomía y Embriología Humanas, leída el 13-01-2016