Publication: Immunocytochemical study on the triple origin of the sphincter iris in the chick embryo
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1999-10
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Barrio Asensio, María del Carmen
Puerta Fonollá, Javier
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Springer-Verlag
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Abstract
The ontogenic development of the sphincter iris has been studied by immunocytochemistry and standard staining on chick embryos from stage 25 HH to the time of hatching. We have used the monoclonal antibody 13F4, a highly specific marker of muscular cells. We have observed three different regions in the iris. Tn the pupillary region, immunoreactive cells are in continuous contact with the inner epithelium of the pupillary margin. In the intermediate region, the outer epithelium forms buds of pigmented cells that emigrate toward the stroma. In this epithelium cells that are totally or partially unpigmented exist, and they are 13F4 positive. In the sphincter we have observed 13F4 positive cells with melanin granules. In the ciliary region, the immunoreactivity appears in dispersed mesenchymal cells. The present findings are consistent with a triple origin of the sphincter iris in the chick embryo. This muscle is derived from the inner epithelium of the pupillary margin, the intermediate region of the outer epithelium, and from the mesenchymal cells. The cells of the inner epithelium of the pupillary margin are differentiated into smooth muscle cells, and the remaining cells form striated muscle cells.
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Received: 17 March 1999 / Accepted: 17 May 1999
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Collin R (1903a) Recherches sur le développement du muscle sphincter de l’iris. Bibl Anat 12:183–196
Collin R (1903b) Premiers stades du développement du muscle sphincter de l’iris chez les oiseaux. C Soc Biol 55:1055–1056
Danilov RK, Ishmeeva ZB (1991) Ultrastructure of the striated muscle tissue of the iris of birds. Arkh Anat Gistol Embriol 100:72–75
1- Ferrari PA, Koch WE (1984) Development of the iris in the chicken embryo I. A study of growth and histodifferentiation utilizing immunocytochemistry for muscle differentiation. J Embryol Exp Morphol 81:153–167
2- Gabella G (1974a) The sphincter pupillae of the guinea-pig. Structure of muscle cells, intercellular relations and density of innervation. Proc R Soc Lond B Biol Sci 186:369–386
3- Gabella G (1974b) Striated muscle cells in the guinea-pig iris. Cell Tissue Res 154:181–188
4- Gabella G, Clarke E (1983) Embryonic development of the smooth and striated musculatures of the chicken iris. Cell Tissue Res 229:37–59
5- Hamburger V, Hamilton HL (1951) A series of normal stages in the development of the chick embryo. J Morphol 88:49–92
6- Lai YL (1972a) The development of the sphincter muscle in the iris of the albino rat. Exp Eye Res 14:196–202
7- Lai YL (1972b) The development of the dilator muscle in the iris of the albino rat. Exp Eye Res 14:203–207
8- Leplat G (1912) Recherches sur le développement et la structure de la membrane vasculaire de l’oeil des oiseaux. Arch Biol (Liége) 27:403–523
9- Lewis WH (1903) Wandering pigmented cells arising from the epithelium of the optic cup, with observations on the origin of the m. sphincter pupillae in the chick. Am J Anat 2:405–416
10- Lucchi ML, Bortolami R, Callegari E (1974) Fine structure of intrinsic eye muscle of birds: development and postnatal changes. J Submicrosc Cytol 6:205–218
11- Marcelle C, Eichmann A, Halevy O, Breant C, Le Douarin N (1994) Distinct developmental expression of a new avian fibroblast growth factor receptor. Development 120:683–694
12- Nakano KE, Nakamura H (1985) Origin of the iridial striated muscle in birds. J Embryol Exp Morphol 88:1–13 14
13- Peirone S, Sisto-Daneo L, Filogamo G (1990) Embryogenesis of the avian iris sphincter muscle: in vivo and in vitro studies. Int J Dev Neurosci 8:17–31
14- Rong PM, Ziller C, Peña-Melián A, Le Douarin N (1987) A monoclonal antibody specific for avian early myogenic cells and differentiated muscle. Dev Biol 122:338–353
15- Rong PM, Teillet MA, Ziller C (1990) Differential influence of the neural primordium on muscle development in myotome and limb. In: The avian model developmental biology: from organism to genes. CNRS, Paris
16- Rong PM, Teillet MA, Ziller C, Le Douarin N (1992) The neural tube/notochord complex is necessary for vertebral but not limb and body wall striated muscle differentiation. Development 115:657–672
17- Scapolo PA, Peirone SM, Filogamo G, Veggetti A (1988) Histochemical, immunohistochemical, and ultrastructural observations on the iris muscles of Gallus gallus. Anat Rec 221:687–699
18- Volpe P, Biral D, Pizzo P, Salviati G, Margreth A (1993) Ontogenesis of chick iris intrinsic muscles: evidence for a smooth-tostriated muscle transition. Dev Biol 159:441–449
19- Yamashita T, Sohal GS (1986) Development of smooth and skeletal muscle cells in the iris of the domestic duck, chick and quail. Cell Tissue Res 244:121–131
20- Yamashita T, Sohal GS (1987) Embryonic origin of skeletal muscle cells in the iris of the duck and quail. Cell Tissue Res 249:31–37
Yang Y, Zalik S (1994) The cells of the dorsal iris involved in lens regeneration are myoepithelial cells whose cytoskeleton changes during cell type conversion. Anat Embryol (Berl) 189:475–487