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Zwitterionic ceramics for biomedical applications

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Izquierdo-Barba, Isabel and Colilla, Montserrat and Vallet Regí, María (2016) Zwitterionic ceramics for biomedical applications. Acta Biomaterialia, 40 . pp. 201-211. ISSN 1742-7061

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Official URL: http://dx.doi.org/10.1016/j.actbio.2016.02.027



Abstract

Bioceramics for bone tissue regeneration, local drug delivery and nanomedicine, are receiving growing attention by the biomaterials scientific community. The design of bioceramics with improved surface properties able to overcome clinical issues is a great scientific challenge. Zwitterionization of surfaces has arisen as a powerful alternative in the design of biocompatible bioceramics capable to inhibit bacterial and non-specific protein adsorption, which opens up new insights into the biomedical applications of these materials. This manuscript reviews the different approaches reported up to date for the synthesis and characterization of zwitterionic bioceramics with potential clinical applications.

Statement of Significance

Zwitterionic bioceramics are receiving growing attention by the biomaterials scientific community due to their great potential in bone tissue regeneration, local drug delivery and nanomedicines. Herein, the different strategies developed so far to synthesize and characterize zwitterionic bioceramics with potential clinical applications are summarized. (C) 2016 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.


Item Type:Article
Additional Information:

RESEARCHER ID M-3378-2014 (María Vallet Regí)
ORCID 0000-0002-6104-4889 (María Vallet Regí)

Uncontrolled Keywords:Zwitterionic bioceramics, functionalization, characterization, Local drug delivery, Bone tissue regeneration, Nanomedicine
Subjects:Sciences > Chemistry
Sciences > Chemistry > Chemical engineering
Sciences > Chemistry > Materials
Sciences > Chemistry > Chemistry, Inorganic
ID Code:40819
Deposited On:31 Jan 2017 09:31
Last Modified:19 Feb 2018 00:01

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