Publication: Características clínicas de pacientes mayores de 65 años diagnosticados de asma: calidad de vida, control de la enfermedad y evolución de la función pulmonar
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2017-02-13
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Universidad Complutense de Madrid
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Abstract
El asma es frecuente en adultos mayores de 65 años, reduciendo sustancialmente la calidad de vida física y psíquica. Constituye un problema creciente debido al envejecimiento de la población. Se caracteriza por estar infradiagnosticada e infratratada, existiendo elementos adicionales de complejidad en lo que se refiere al diagnóstico y tratamiento, particularmente la presencia de comorbilidades, que pueden influir en la mayor morbi-mortalidad de este grupo de población. Los asmáticos de edad avanzada tienen un mayor riesgo de comorbilidades y diferentes estudios encuentran una asociación entre asma mal controlada y comorbilidades, aunque se sabe poco acerca de la combinación de múltiples patologías crónicas con el asma. Objetivos Los objetivos generales de este estudio son evaluar las características clínicas y funcionales de los pacientes con asma y mayores de 65 años y valorar el efecto de las mismas, especialmente la presencia de diferentes comorbilidades sobre el control del asma, la calidad de vida y la función pulmonar. Los objetivos específicos son: 1. Determinar las características clínicas y funcionales en pacientes mayores de 65 años diagnosticados de asma. 2. Analizar si la presencia de diferentes características clínicas, particularmente, género, atopia, duración y gravedad de la enfermedad, presencia de comorbilidades y exacerbaciones graves o la función pulmonar modifican el control del asma medido por cuestionarios validados (ACT). 3. Analizar si la presencia de diferentes características clínicas, particularmente, género, atopia, duración y gravedad de la enfermedad, presencia de comorbilidades y exacerbaciones graves o la función pulmonar modifican la percepción de la calidad de vida medida por cuestionarios de calidad de vida validados (AQLQ)...
Asthma is common in individuals aged 65 years and older and it substantially reduces both psychological and physical quality of life. Asthma in the elderly (AIE) is an emerging problem as the population of the world is ageing. Frequently AIE is underdiagnosed and undertreated, showing additional elements of complexity on the diagnosis and management, particularly the presence of comorbid conditions which can influence the increased morbidity and mortality in this population. Elderly asthmatics have a higher risk of comorbidities and different studies have found an association between poorly controlled asthma and comorbidities, but little is known about the combination of multiple chronic diseases with asthma. Objectives The aim of this study was to evaluate clinical and functional characteristics of asthmatic patients aged 65 and over and analyze the effect of those particularly comorbid conditions on asthma control, quality of life and lung function. 1. To determine clinical and functional characteristics of asthmatic patients aged 65 or over. 2. To analyze if clinical characteristics particularly gender, atopy, severity, duration of disease, comorbid conditions, severe exacerbations, and lung function modifies asthma control assessed by validated questionnaires Asthma Control Test (ACT). 3. To analyze if clinical characteristics particularly gender, atopy, severity, duration of disease, comorbid conditions, severe exacerbations, and lung function modifies perception of quality of life assessed by validated health-related quality of life questionnaire (AQLQ)...
Asthma is common in individuals aged 65 years and older and it substantially reduces both psychological and physical quality of life. Asthma in the elderly (AIE) is an emerging problem as the population of the world is ageing. Frequently AIE is underdiagnosed and undertreated, showing additional elements of complexity on the diagnosis and management, particularly the presence of comorbid conditions which can influence the increased morbidity and mortality in this population. Elderly asthmatics have a higher risk of comorbidities and different studies have found an association between poorly controlled asthma and comorbidities, but little is known about the combination of multiple chronic diseases with asthma. Objectives The aim of this study was to evaluate clinical and functional characteristics of asthmatic patients aged 65 and over and analyze the effect of those particularly comorbid conditions on asthma control, quality of life and lung function. 1. To determine clinical and functional characteristics of asthmatic patients aged 65 or over. 2. To analyze if clinical characteristics particularly gender, atopy, severity, duration of disease, comorbid conditions, severe exacerbations, and lung function modifies asthma control assessed by validated questionnaires Asthma Control Test (ACT). 3. To analyze if clinical characteristics particularly gender, atopy, severity, duration of disease, comorbid conditions, severe exacerbations, and lung function modifies perception of quality of life assessed by validated health-related quality of life questionnaire (AQLQ)...
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Tesis inédita de la Universidad Complutense de Madrid, Facultad de Medicina, Departamento de Medicina, leída el 10-02-2016