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Importance of the Geographic Barriers to PromoteGene Drift and Avoid Pre- and Post-Col umbian GeneFlow in Mexican Native Groups: Evidence from Forensic STR Loci

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Rangel Villalobos, Héctor y Martínez Sevilla, Victor Manuel y Martínez Cortés, Gabriela y Aguilar Velázquez, José Alonso y Sosa Macías, Martha y Rubí Castellanos, Rodrigo y González Martín, Antonio (2016) Importance of the Geographic Barriers to PromoteGene Drift and Avoid Pre- and Post-Col umbian GeneFlow in Mexican Native Groups: Evidence from Forensic STR Loci. American journal of physical anthropology, 160 (2). pp. 298-316. ISSN 0002-9483, ESSN: 1096-8644

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URL Oficial: http://onlinelibrary.wiley.com/doi/10.1002/ajpa.22969/full



Resumen

Objective: To analyze the origin, structure,relationships, and recent admixture in Mexican Native groups basedon 15 STRs commonly used in human identification.
Methods: We analyzed 39 Mexican Native population samples using STR databases based on the AmpFlSTRVRIdentifiler kit (n=3,135), including Mexican-Mestizos (admixed),European and African populations, as reference.
Results: Based upon effective population size (Ne) differences, Native groups were clustered into three regions: i)Center-Southeast groups, characterized by larger Ne, migration rate (Nm), genetic diversity (He), and relative homo-geneity principally in the Yucatan Peninsula; ii) Isolated southern groups from Chiapas and Oaxaca, characterizedby lower Ne, Nm, and He (i.e. higher isolation and genetic differentiation); iii) North-Northwest groups, which aresimilar to the previous group but are characterized by generating the widest gene flow barrier in the Pre-HispanicMexican territory, and currently by elevated admixture in some northern Native groups. Despite the relative congru-ence between genetic relationships with cultural, linguistic, geographic criteria, these factors do not explain thepresent-day population structure of Native groups, excepting in those linguistically related to the Mayan that showhigher homogeneity. The Isolation by distance model was demonstrated at long distances (>1,500 km), whereas geo-graphic isolation stands as a determining factor to avoid both non-indigenous admixture and bottleneck processes.
Conclusions: Different dynamics of gene flow and drift were observed among Mexican Native groups, highlight-ing the geographic barriers (mountains, canyons and jungle regions) as the main factor differentiating Pre-hispanicpopulations, and eventually helping to avoid Post-European contact admixture and population bottleneck.


Tipo de documento:Artículo
Palabras clave:STRs; Mexico; Amerindians; gene drift; admixture; structure
Materias:Ciencias Biomédicas > Biología > Antropología biológica
Código ID:41421
Depositado:21 Feb 2017 09:07
Última Modificación:05 Mar 2018 16:03

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