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Electron microscopy for inorganic-type drug delivery nanocarriers for antitumoral applications: What is possible to see?

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Baeza García, Alejandro and Castillo Romero, Rafael and Torres Pardo, Almudena and Gonzalez Calvet, J. M. and Vallet Regí, María (2017) Electron microscopy for inorganic-type drug delivery nanocarriers for antitumoral applications: What is possible to see? Journal of Materials Chemistry B . ISSN 2050-750X (In Press)

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Abstract

The use of nanoparticles able to transport drugs, in a selective and controlable manner, directly to diseased tissues and cells have improved the therapeutic arsenal for addressing unmet clinical situations. In the recent years, a vast number of nanocarriers with inorganic, organic, hybrid and even biological nature have been developed, expecially for their application in oncology fied. The exponential growing in the nanomedicine field would not have been possible without the also rapid expansion of electron microscopy techniques, which allow a more precise observation of nanometric objects. The use of these techniques provides a better understanding of the key parameters which rule their synthesis and behavior. In this review, the recent advances performed in the application of inorganic nanoparticles for clinical uses and the role which has played electron microscopy will be presented.


Item Type:Article
Additional Information:

RESEARCH ID L-2854-2014  (Rafael Castillo Romero)
ORCID 0000-0003-1957-3098 (Rafael Castillo Romero)
RESEARCH ID    K-8193-2014  (Alejandro Baeza García)
ORCID 0000-0002-9042-8865 (Alejandro Baeza García)
RESEARCH ID M-3378-2014 (María Vallet Regí)
ORCID 0000-0002-6104-4889 (María Vallet Regí)

Uncontrolled Keywords:Nanocarriers antitumoral applications, Electron microscopy
Subjects:Medical sciences > Pharmacy > Inorganic chemistry
ID Code:41661
Deposited On:03 Apr 2017 09:39
Last Modified:18 Feb 2018 00:01

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