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The neuroprotective actions of oestradiol and oestrogen receptors

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Arévalo, María Ángeles y Azcoitia Elías, Iñigo y García Segura, Luis Miguel (2015) The neuroprotective actions of oestradiol and oestrogen receptors. Nature Reviews Neuroscience, 16 . pp. 17-29. ISSN 1471-003X

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URL Oficial: http://www.nature.com/nrn/index.html



Resumen

Hormones regulate homeostasis by communicating through the bloodstream to the body’s organs, including the brain. As homeostatic regulators of brain function, some hormones exert neuroprotective actions. This is the case for the ovarian hormone 17β‑oestradiol, which signals through oestrogen receptors (ERs) that are widely distributed in the male and female brain. Recent discoveries have shown that oestradiol is not only a reproductive hormone but also a brain-derived neuroprotective factor in males and females and that ERs coordinate multiple signalling mechanisms that protect the brain from neurodegenerative diseases, affective disorders and cognitive decline.


Tipo de documento:Artículo
Palabras clave:Biología Celular, Hormonas, 17β‑oestradiol, Citología
Materias:Ciencias Biomédicas > Biología > Biología celular
Código ID:41772
Depositado:13 Mar 2017 16:08
Última Modificación:10 May 2017 08:04

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