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Differences in Dry Eye Questionnaire Symptoms in Two Different Modalities of Contact Lens Wear: Silicone-Hydrogel in Daily Wear Basis and Overnight Orthokeratology

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García Porta, Nery and Rico del Viejo, Laura and Martín Gil, Alba and Carracedo Rodríguez, Juan Gonzalo and Pintor, Jesús and González-Méijome, José Manuel (2016) Differences in Dry Eye Questionnaire Symptoms in Two Different Modalities of Contact Lens Wear: Silicone-Hydrogel in Daily Wear Basis and Overnight Orthokeratology. BioMed Research International, 2016 (124284). 9 p.. ISSN 2314-6133

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Official URL: http://dx.doi.org/10.1155/2016/1242845




Abstract

Purpose. To compare the ocular surface symptoms and signs in an adult population of silicone-hydrogel (Si-Hy) contact lens (CL) wearers with another modality of CL wear, overnight orthokeratology (OK). Materials and Methods. This was a prospective and comparative study in which 31 myopic subjects were fitted with the same Si-Hy CL and 23 underwent OK treatment for 3 months. Dry eye questionnaire (DEQ) was filled in at the beginning of the study and then after 15 days, 1 month, and 3 months using each CL modality. The tear quality was evaluated with noninvasive tear break-up time. Tear production was measured with Schirmer test. Tear samples were collected with Schirmer strips being frozen to analyze the dinucleotide diadenosine tetraphosphate (Ap4A) concentration with High-Performance Liquid Chromatography (HPLC). Results. After refitting with ortho-k, a reduction in discomfort and dryness symptoms at the end of the day (, ) was observed. No significant changes were observed in Ap4A concentration in any group. Bulbar redness, limbal redness, and conjunctival staining increased significantly in the Si-Hy group (, Kruskal–Wallis test). Conclusion. Discomfort and dryness symptoms at the end of the day are lower in the OK CL group than in the Si-Hy CL group.


Item Type:Article
Additional Information:

Received 3 May 2016; Revised 31 July 2016; Accepted 1 August 2016

Uncontrolled Keywords:Dry eye ; Contact Lens ; Silicone-hydrogel lens ; Orthokeratology ; Ocular surface
Subjects:Medical sciences > Optics > Contact lenses
Medical sciences > Optics > Optometry
Medical sciences > Optics > Visual perception
ID Code:41806
Deposited On:14 Mar 2017 10:53
Last Modified:14 Mar 2017 10:53

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