Publication: Incidencia de linfedema en cáncer de mama precoz. Diferencias entre biopsia selectiva de ganglio centinela y linfadenectomía
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2017-09-01
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Universidad Complutense de Madrid
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Abstract
El linfedema es una patología crónica, infradiagnosticada e infratratada, secundaria a los tratamientos del cáncer de mama. Es una enfermedad crónica, cuyos efectos inciden en la calidad de vida del paciente de forma importante. RESUMEN El cáncer de mama precoz se define como una enfermedad localizada en la mama, con o sin afectación de los ganglios linfáticos regionales y con ausencia de enfermedad metastásica a distancia. El término se basa en el hecho de que el CMP es potencialmente curable y los pacientes con enfermedad metastásica a distancia no lo son. OBJETIVO E HIPÓTESIS En el diagnóstico y tratamiento del cáncer de mama precoz, la biopsia selectiva del ganglio centinela se ha convertido en un componente diagnóstico esencial y es en la actualidad el procedimiento de elección para la estadificación axilar. Esta técnica es una herramienta fundamental que puede reducir la necesidad de una segunda intervención quirúrgica en las pacientes con un ganglio centinela negativo. La frecuente aparición de linfedema en el miembro afecto tras la cirugía del cáncer de mama y las limitantes consecuencias derivadas del mismo, justifican la necesidad de profundizar en el estudio de su incidencia, para poder ofrecer a las pacientes las diferentes técnicas que se aplican en el tratamiento. El conocimiento de estas técnicas y sus consecuencias sobre el miembro superior, nos servirán para orientar la necesidad de futura rehabilitación y la planificación de las necesidades terapéuticas que requieran según el tipo de tratamiento aplicado. Esta tesis pretende describir la incidencia de aparición de linfedema en una población objeto de estudio de 158 pacientes, 78 sometidas a biopsia selectiva del ganglio centinela sólo y 80 a biopsia selectiva del ganglio centinela más linfadenectomía...
Lymphoedema is an underdiagnosed and undertreated chronical pathology that appears as a side effect of breast canceŕs treatment, It́s a chronical disease whose effects have a great impact in the quality of life of the patients. ABSTRACT Early breast canccer can be defined as a localized disease in the breast, with or without regionals lymph nodes affectation and wthout distant metastasic disease. The term “Early Breast Cancer” is used for the disease which can be cured in contrast to distant metastasic disease which can not. OBJETIVES AND HYPOTHESIS The selective sentinel lymph node biopsy is an essential component for the diagnosis in the early breast cancer and the gold standard procedure for the axillar staging. This technic is a fundamental tool that can reduce the need for a second surgery in patients with negative sentinel lymph node. The frequent development of lymphedema in affected side after breast cancer surgery and the consequences that derive from it justify the need of further study of its incidence. This way, better treatment can be offered to the patients. The knowledge of these techniques and the consequences for the upper limb of their application are helpful to plan a future rehabilitation program and other therapeutic needs according to the applied treatment. This thesis describes the incidence of development of lymphedema in a sample of 158 patients, 78 of them treated with only selective sentinel lymph node and 80 of them treated with selective sentinel lymph node biopsy plus lymphadenectomy. This study aims to explore the causality between risk factors and lymphedema...
Lymphoedema is an underdiagnosed and undertreated chronical pathology that appears as a side effect of breast canceŕs treatment, It́s a chronical disease whose effects have a great impact in the quality of life of the patients. ABSTRACT Early breast canccer can be defined as a localized disease in the breast, with or without regionals lymph nodes affectation and wthout distant metastasic disease. The term “Early Breast Cancer” is used for the disease which can be cured in contrast to distant metastasic disease which can not. OBJETIVES AND HYPOTHESIS The selective sentinel lymph node biopsy is an essential component for the diagnosis in the early breast cancer and the gold standard procedure for the axillar staging. This technic is a fundamental tool that can reduce the need for a second surgery in patients with negative sentinel lymph node. The frequent development of lymphedema in affected side after breast cancer surgery and the consequences that derive from it justify the need of further study of its incidence. This way, better treatment can be offered to the patients. The knowledge of these techniques and the consequences for the upper limb of their application are helpful to plan a future rehabilitation program and other therapeutic needs according to the applied treatment. This thesis describes the incidence of development of lymphedema in a sample of 158 patients, 78 of them treated with only selective sentinel lymph node and 80 of them treated with selective sentinel lymph node biopsy plus lymphadenectomy. This study aims to explore the causality between risk factors and lymphedema...
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Tesis inédita de la Universidad Complutense de Madrid, Facultad de Medicina, Departamento de Medicina Física y de Rehabilitación. Hidrología Médica, leída el 02-02-2016