Universidad Complutense de Madrid
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Changes in corneal biomechanical properties after 24 hours of continuous intraocular pressure monitoring using a contact lens sensor

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Morales Fernández, Laura y García Bella, Javier y Martínez de la Casa, Jose Maria y Sánchez Jean, Rubén y Sáenz Francés, Federico y Arriola Villalobos, Pedro y Perucho González, Lucía y Santos Bueso, Enrique y García Feijoo, Julián (2017) Changes in corneal biomechanical properties after 24 hours of continuous intraocular pressure monitoring using a contact lens sensor. Canadian Journal of Ophthalmology . 5 p.. ISSN 1715-3360 (En prensa)

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URL Oficial: http://dx.doi.org/10.1016/j.jcjo.2017.10.028




Resumen

Objective: This study was designed to assess changes in corneal topography and biomechanics after intraocular pressure (IOP) monitoring using the Triggerfish contact lens sensor (CLS).
Methods: For this prospective study, 30 eyes of 30 subjects: 14 healthy subjects (G1) and 6 glaucoma patients (G2), were recruited for 24 hours of continuous IOP monitoring using the CLS. The following measurements were taken before CLS fitting and after lens removal: maximum keratometry (Kmax), mean keratometry (MK), and corneal astigmatism (Cyl) measured through Pentacam corneal topography, and the corneal biomechanical variables corneal hysteresis (CH) and corneal resistance factor (CRF) measured with the Ocular Response Analyzer (ORA).
Results: Pentacam data revealed significant changes after CLS removal in Kmax (+3.14 ± 2.46 D, p = 0.002), MK (+0.52 ± 0.63 D, p = 0.02), and Cyl (+0.48 ± 0.53 D, p = 0.019) in G1; and Kmax (+1.38 ± 1.43 D, p = 0.002) in G2. The changes observed were more pronounced in G1 than in G2 but differences were not significant. The ORA results indicated higher CH (11.35 ± 2.42 vs 8.17 ± 2.09) and CRF (10.3 ± 2.03 vs 9.1 ± 1.81) before lens fitting in G1 than G2, while no significant changes were produced after CLS removal in either group.
Conclusions: The use of CLS for IOP monitoring over 24 hours caused topographic changes in both healthy subjects and glaucoma patients. No changes were produced in corneal biomechanics.


Tipo de documento:Artículo
Información Adicional:

Received 17 April 2017, Revised 5 October 2017, Accepted 10 October 2017, Available online 18 December 2017.

Palabras clave:Cornea; Intraocular pressure; Contact lens sensor; Corneal biomechanical properties; Glaucoma; Corneal topography; Pentacam;
Materias:Ciencias Biomédicas > Medicina > Oftalmología
Ciencias Biomédicas > Óptica y optometría > Lentes de contacto
Ciencias Biomédicas > Óptica y optometría > Técnicas de la imagen
Código ID:46071
Depositado:22 Ene 2018 13:34
Última Modificación:18 Dic 2018 00:01

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