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Agreement and clinical comparison between a new swept-source optical coherence tomography-based optical biometer and an optical low-coherence reflectometry biometer

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Arriola Villalobos, Pedro and Almendral Gómez, Jaime and Garzón Jiménez, Nuria and Ruiz Medrano, Jorge and Fernández Pérez, Cristina and Martínez de la Casa, Jose Maria and Díaz Valle, David (2017) Agreement and clinical comparison between a new swept-source optical coherence tomography-based optical biometer and an optical low-coherence reflectometry biometer. Eye, 31 (3). pp. 437-442. ISSN 0950-222X

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Official URL: http://dx.doi.org/10.1038/eye.2016.241




Abstract

Purpose To compare measurements taken using a swept-source optical coherence tomography-based optical biometer (IOLmaster 700) and an optical low-coherence reflectometry biometer (Lenstar 900), and to determine the clinical impacts of differences in their measurements on intraocular lens (IOL) power predictions. Methods Eighty eyes of 80 patients scheduled to undergo cataract surgery were examined with both biometers. The measurements made using each device were axial length (AL), central corneal thickness (CCT), aqueous depth (AQD), lens thickness (LT), mean keratometry (MK), white-to-white distance (WTW), and pupil diameter (PD). Holladay 2 and SRK/T formulas were used to calculate IOL power. Differences in measurement between the two biometers were determined using the paired t-test. Agreement was assessed through intraclass correlation coefficients (ICC) and Bland-Altman plots. Results Mean patient age was 76.3±6.8 years (range 59-89). Using the Lenstar, AL and PD could not be measured in 12.5 and 5.25% of eyes, respectively, while IOLMaster 700 took all measurements in all eyes. The variables CCT, AQD, LT, and MK varied significantly between the two biometers. According to ICCs, correlation between measurements made with both devices was excellent except for WTW and PD. Using the SRK/T formula, IOL power prediction based on the data from the two devices were statistically different, but differences were not clinically significant. Conclusions No clinically relevant differences were detected between the biometers in terms of their measurements and IOL power predictions. Using the IOLMaster 700, it was easier to obtain biometric measurements in eyes with less transparent ocular media or longer AL.


Item Type:Article
Additional Information:

Received: 11 April 2016; Accepted: 07 September 2016; Published online: 11 November 2016

Uncontrolled Keywords:Lens diseases; Physycal examination; Optica biometer; Optical coherence tomography; Intraocular lens
Subjects:Medical sciences > Medicine > Surgery
Medical sciences > Medicine > Diagnostic imaging and Nuclear medicine
Medical sciences > Medicine > Ophtalmology
Medical sciences > Optics > Visual perception
ID Code:47113
Deposited On:11 Apr 2018 12:15
Last Modified:11 Apr 2018 15:15

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