Publication: Marcadores tumorales: presente y futuro
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2015-06
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Abstract
El cáncer es la segunda enfermedad no transmisible que más muertes produce al año a nivel mundial. A pesar de los avances de las últimas décadas, aún existe un amplio margen de mejora en el diagnóstico, pronóstico y monitorización de la enfermedad, así como en la detección de recidivas. Los marcadores tumorales juegan un importante papel en estos aspectos, empleándose en la actualidad una veintena de ellos en la práctica clínica. Sin embargo, estas moléculas presentan ciertas limitaciones que están llevando a los investigadores a estudiar nuevas posibilidades, como la utilidad del material genético circulante como marcador tumoral más preciso. En este trabajo se realizó una revisión bibliográfica sobre los marcadores empleados en la actualidad en cánceres comunes en nuestro país y sobre algunos de aquéllos que podrían, en un futuro cercano, constituir una herramienta para incrementar las tasas de curación de esta enfermedad
Cancer is the second non-communicable disease that causes more deaths worldwide annually. Despite the advances of recent decades, there is still ample room for improvement in the diagnosis, prognosis and monitoring of disease, as well as in detecting recurrences. Tumor markers play an important role in these areas, and twenty of them are used in clinical practice nowadays. However, these molecules have limitations that are leading the researchers to study new possibilities such as the utility of circulating genetic material as a more accurate tumor marker. This paper presents a literature review on the markers used currently in common cancers in our country and some of those that could, in the near future, be a tool for increasing cure rates of this disease.
Cancer is the second non-communicable disease that causes more deaths worldwide annually. Despite the advances of recent decades, there is still ample room for improvement in the diagnosis, prognosis and monitoring of disease, as well as in detecting recurrences. Tumor markers play an important role in these areas, and twenty of them are used in clinical practice nowadays. However, these molecules have limitations that are leading the researchers to study new possibilities such as the utility of circulating genetic material as a more accurate tumor marker. This paper presents a literature review on the markers used currently in common cancers in our country and some of those that could, in the near future, be a tool for increasing cure rates of this disease.