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The role of zwitterionic materials in the fight against proteins and bacteria

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Colilla Nieto, Montserrat y Izquierdo Barba, Isabel y Vallet-Regí, María (2018) The role of zwitterionic materials in the fight against proteins and bacteria. MEDICINES, 5(4) . p. 125. ISSN 2305-6320

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URL Oficial: https://www.mdpi.com/journal/medicines


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http://www.ucm.es/valletregigroupSIN ESPECIFICAR


Resumen

Zwitterionization of biomaterials has been heightened to a potent tool to develop biocompatible materials able to inhibit bacterial and non-specific proteins adhesion. This constitutes a major progress in the biomedical field. This manuscript overviews the main functionalization strategies that have been reported up to date to design and develop these advanced biomaterials. On this regard, the recent research efforts dedicated to provide their surface of zwitterionic nature are summarized by classifying biomaterials in two main groups. First, we centre on biomaterials in clinical use, concretely bioceramics and metallic implants. Finally, we revise emerging nanostructured biomaterials, which are receiving growing attention due to their multifunctionality and versatility mainly in the local drug delivery and bone tissue regeneration scenarios.


Tipo de documento:Artículo
Información Adicional:

RESEARCHER ID N-4628-2014 (Montse Colilla Nieto)
ORCID 0000-0003-1961-4160 (Montse Colilla Nieto)
RESEARCHER ID M-9921-2014 (Isabel Izquierdo Barba)
ORCID 0000-0002-4139-4646 (Isabel Izquierdo Barba)
RESEARCHER ID M-3378-2014 (María Vallet Regí)
ORCID 0000-0002-6104-4889 (María Vallet Regí)

Palabras clave:Biomaterials; zwitterionic surfaces; infection; bioceramics; bacterial inhibition.
Materias:Ciencias > Química > Materiales
Código ID:50361
Depositado:11 Ene 2019 09:28
Última Modificación:11 Ene 2019 11:19

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