Publication: Estudio de utilización de antifúngicos restringidos en el hospital clínico de San Carlos
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Publication Date
2019-01-30
Authors
Manzano Lorenzo, Rocío
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Merino Amador, Paloma
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Universidad Complutense de Madrid
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Abstract
El uso adecuado de antibióticos tiene un impacto muy importante sobre la disminución de la morbilidad y mortalidad en los procesos infecciosos. Sin embargo, diversos estudios muestran un uso inadecuado de antifúngicos que oscila desde un 40% hasta un 70%. Las recomendaciones actuales promueven la implantación de programas de optimización de uso de antimicrobianos o “Antimicrobial stewardship” que buscan promover el uso correcto de antibióticos mediante la selección del antimicrobiano más indicado, dosis, vía de administración y duración del tratamiento adecuados a través de la formación de grupos multidisciplinares. Generalmente estos programas de optimización de uso se han centrado en los tratamientos antibacterianos principalmente, dejando de lado los antifúngicos, a pesar de las deficiencias que existen en la prescripción de estos fármacos. Los beneficios esperados de estos programas son la mejora en el tratamiento de las infecciones fúngicas haciendo uso de la terapia más coste–efectiva...
The appropriate use of antibiotics has a very significant impact on the reduction of morbidity and mortality in infectious processes. However, several studies have shown an inadequate use of antifungals ranging from 40% to 70%.Current recommendations promote the implementation of optimization programmes for the use of antimicrobials or, in other words, antimicrobial stewardship which seek to promote the correct use of antibiotics through selection of the most indicated antimicrobial, as well as adequate dose, administration route and length of treatment through the creation of multidisciplinary groups. Generally, these use optimization programmes have primarily focused on antibacterial treatment, neglecting antifungals, despite existing deficiencies in the prescription of these drugs. Expected benefits of these programmes are improvement of fungal infections by implementing the most cost-effective therapy...
The appropriate use of antibiotics has a very significant impact on the reduction of morbidity and mortality in infectious processes. However, several studies have shown an inadequate use of antifungals ranging from 40% to 70%.Current recommendations promote the implementation of optimization programmes for the use of antimicrobials or, in other words, antimicrobial stewardship which seek to promote the correct use of antibiotics through selection of the most indicated antimicrobial, as well as adequate dose, administration route and length of treatment through the creation of multidisciplinary groups. Generally, these use optimization programmes have primarily focused on antibacterial treatment, neglecting antifungals, despite existing deficiencies in the prescription of these drugs. Expected benefits of these programmes are improvement of fungal infections by implementing the most cost-effective therapy...
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Tesis de la Universidad Complutense de Madrid, Facultad de Medicina, Departamento de Medicina, leída el 21/06/2018