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Effect of illuminating wavelength on the contrast of meibography images

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Peral Cerdá, Assumpta and Alonso Fernández, José and Gómez Pedrero, Jose Antonio (2018) Effect of illuminating wavelength on the contrast of meibography images. OSA Continuum, 1 (3). ISSN 2578-7519

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Official URL: https://doi.org/10.1364/OSAC.1.001041




Abstract

Evaluation of the Meibomian glands morphology is becoming a popular assessment for dry eye. This evaluation is usually done by imaging the glands on the everted lids while they are illuminated with infrared light. Nowadays techniques to determine gland condition and dropout are based on grading scales with which meibography images are subjectively evaluated. In this work, we have measured the contrast of Meibomian gland images from ten subjects and for a range of wavelengths of the monochromatic illuminating light. We have used a xenon lamp and a monochromator as a light source, and a semi-automatic image processing technique for measuring the image contrast from 600 nm to 1050 nm. Contrast values inside glands are from 0.025 to 0.015 and between glands from 0.06 to 0.04. The greater values of contrast are obtained when Meibomian glands are illuminated with a wavelength close to 600 nm.


Item Type:Article
Additional Information:

© 2018 Optical Society of America under the terms of the OSA Open Access Publishing Agreement
Received 6 Jul 2018; revised 5 Oct 2018; accepted 11 Oct 2018; published 13 Nov 2018

Uncontrolled Keywords:Contact lenses; Image processing; Image processing algorithms; Imaging techniques; Nonlinear spatial; Filtering; Visible light
Subjects:Medical sciences > Medicine > Diagnostic imaging and Nuclear medicine
Medical sciences > Optics > Eyes anatomy
Medical sciences > Optics > Imaging systems
Medical sciences > Optics > Nonlinear optics
ID Code:51193
Deposited On:14 Feb 2019 13:51
Last Modified:18 Feb 2019 08:51

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