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Detection of Histamine Dihydrochloride at Low Concentrations Using Raman Spectroscopy Enhanced by Gold Nanostars Colloids

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Kolosovas Machuca, Eleazar Samuel and Cuadrado Conde, Alexander and Ojeda Galván, Hiram Joazet and Ortiz Dosal, Luis Carlos and Hernández Arteaga, Aida Catalina and Rodríguez Aranda, María del Carmen and Navarro Contreras, Hugo Ricardo and Alda, Javier and González Contreras, Francisco Javier (2019) Detection of Histamine Dihydrochloride at Low Concentrations Using Raman Spectroscopy Enhanced by Gold Nanostars Colloids. Nanomaterials, 9 (2). 11 p.. ISSN 2079-4991

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Official URL: https://doi.org/10.3390/nano9020211




Abstract

In this paper, we report a fast and easy method to detect histamine dihydrochloride using gold nanostars in colloidal aqueous solution as a highly active SERS platform with potential applications in biomedicine and food science. This colloid was characterized with SEM and UV–Vis spectroscopy. Also, numerical calculations were performed to estimate the plasmonic resonance and electric field amplification of the gold nanoparticles to compare the difference between nanospheres and nanostars. Finally, aqueous solutions of histamine dihydrochloride were prepared in a wide range of concentrations and the colloid was added to carry out SERS. We found SERS amplified the Raman signal of histamine by an enhancement factor of 1.0 × 10 7 , demonstrating the capability of the method to detect low concentrations of this amine molecule.


Item Type:Article
Additional Information:

Received: 20 December 2018 / Revised: 16 January 2019 / Accepted: 22 January 2019 / Published: 6 February 2019
(This article belongs to the Special Issue Biomedical Applications of Nanoparticles)

Uncontrolled Keywords:SERS; histamine; nanostars; nanophotonics; computational electromagnetism
Subjects:Sciences > Physics > Optics
Medical sciences > Optics > Imaging systems
ID Code:51299
Deposited On:20 Feb 2019 11:40
Last Modified:20 Feb 2019 11:40

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