Publication: Predictores de la mortalidad intrahospitalaria en pacientes con "Shock" cardiogénico: implicaciones pronósticas y terapéuticas
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2019-02-18
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Universidad Complutense de Madrid
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Abstract
El shock cardiogénico presenta un mal pronóstico. La mortalidad del shock cardiogénico continúa siendo muy alta a pesar de los avances terapéuticos producidos durante los últimos años. Sin embargo, la heterogeneidad en la mortalidad en los diferentes subgrupos de pacientes con shock cardiogénico sugiere que existen determinados factores que podrían ser útiles en la estratificación del riesgo y la selección de la opción terapéutica más adecuada para pacientes con esta emergencia médica. El objetivo de este estudio es investigar sobre la relación entre el perfil clínico y el resultado de pacientes con shock cardiogénico para encontrar predictores de la mortalidad intrahospitalaria en estos pacientes. Métodos. En el presente estudio se analizaron retrospectivamente los pacientes con diagnóstico de shock cardiogénico debido a enfermedades médicas ingresados en la Unidad de Cuidados Intensivos Cardiológicos de un centro hospitalario terciario, el Hospital General Universitario Gregorio Marañón, desde noviembre de 2010 hasta noviembre de 2015. Los pacientes incluidos presentaban una edad de 18 años o superior. La etiología del shock cardiogénico no se limitó solo al síndrome coronario agudo, sino que otras causas de shock cardiogénico también fueron incluidas. Se recogieron variables clínicas, bioquímicas y hemodinámicas, así como el tratamiento médico o invasivo recibido durante la hospitalización...
Cardiogenic shock has a poor prognosis. The mortality of cardiogenic shock remains high despite the therapeutics advances that occurred in this field during the last years. The heterogeneity in the mortality through different subgroups suggests that some factors can be useful to perform risk stratification and guide management of this medical emergency. We aimed to investigate the relationship between clinical profile and outcomes of patients with cardiogenic shock in order to find predictors of in-hospital mortality in these patients. Methods. We retrospectively analysed all cases of cardiogenic shock due to medical conditions admitted in the intensive acute cardiac care unit at a tertiary center, Gregorio Marañón General University Hospital, from November 2010 till November 2015. Patients who were 18 years of age or older were enrolled. The etiology of cardiogenic shock was not restricted to acute myocardium infarction, as other causes of cardiogenic shock were also included as well. Clinical, biochemical and hemodynamic variables were registered, as was the medical or invasive treatment received during the hospitalization...
Cardiogenic shock has a poor prognosis. The mortality of cardiogenic shock remains high despite the therapeutics advances that occurred in this field during the last years. The heterogeneity in the mortality through different subgroups suggests that some factors can be useful to perform risk stratification and guide management of this medical emergency. We aimed to investigate the relationship between clinical profile and outcomes of patients with cardiogenic shock in order to find predictors of in-hospital mortality in these patients. Methods. We retrospectively analysed all cases of cardiogenic shock due to medical conditions admitted in the intensive acute cardiac care unit at a tertiary center, Gregorio Marañón General University Hospital, from November 2010 till November 2015. Patients who were 18 years of age or older were enrolled. The etiology of cardiogenic shock was not restricted to acute myocardium infarction, as other causes of cardiogenic shock were also included as well. Clinical, biochemical and hemodynamic variables were registered, as was the medical or invasive treatment received during the hospitalization...
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Tesis de la Universidad Complutense de Madrid, Facultad de Medicina, Departamento de Medicina, leída el 11/10/2018