Publication: Estreñimiento en el niño en estado crítico
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2019-02-19
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Universidad Complutense de Madrid
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Abstract
El estreñimiento es una complicación frecuente pero poco estudiada en el paciente en estado crítico. Su diagnóstico frecuentemente se retrasa ya que es considerado como una complicación poco relevante en estos pacientes. Sin embargo en adultos, el estreñimiento se ha asociado con un aumento de la morbimortalidad. No hay estudios previos que hayan definido claramente los criterios diagnósticos, factores de riesgo, utilidad de las pruebas complementarias ni la efectividad de los tratamientos para el estreñimiento en el niño en estado crítico. Los objetivos de este estudio son analizar la incidencia y los factores relacionados con el estreñimiento en el niño en estado crítico; desarrollar y validar una escala que permita el diagnóstico precoz del mismo; estudiar la utilidad de la prueba del hidrógeno espirado (eH2) tras ingesta de lactulosa para evaluar el tránsito gastrocecal; y analizar la efectividad y seguridad de un protocolo de tratamiento con polietilenglicol (PEG) con iones en estos pacientes...
Constipation is a common but understudied complication in the critically ill child. Its diagnosis is frequently delayed due to it is considered a less severe complication in these patients. However, constipation has been associated with worse outcomes incritically ill adults. There are no studies in critically ill children focused on risk factors,diagnostic criteria, diagnostic tests or treatments for constipation. The aims of this study are to describe the incidence and factors associated with constipation in critically ill children; to develop and validate a clinical score that allows early diagnosis; to study the usefulness of the expired hydrogen (eH2) breath test after ingestion of lactulose to evaluate the gastrocecal transit; and to analyze the effectiveness and safety of a treatment protocol with polyethylene glycol (PEG) with ions in these patients...
Constipation is a common but understudied complication in the critically ill child. Its diagnosis is frequently delayed due to it is considered a less severe complication in these patients. However, constipation has been associated with worse outcomes incritically ill adults. There are no studies in critically ill children focused on risk factors,diagnostic criteria, diagnostic tests or treatments for constipation. The aims of this study are to describe the incidence and factors associated with constipation in critically ill children; to develop and validate a clinical score that allows early diagnosis; to study the usefulness of the expired hydrogen (eH2) breath test after ingestion of lactulose to evaluate the gastrocecal transit; and to analyze the effectiveness and safety of a treatment protocol with polyethylene glycol (PEG) with ions in these patients...
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Tesis de la Universidad Complutense de Madrid, Facultad de Medicina, leída el 13-12-2018