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Functional Mesoporous Silica Nanocomposites: Biomedical applications and Biosafety

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Castillo, Rafael R. and Vallet Regí, María (2019) Functional Mesoporous Silica Nanocomposites: Biomedical applications and Biosafety. International Journal of Molecular . ISSN 1422-0067 (In Press)

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Abstract

The rise and development of nanotechnology has permitted to create of a wide number of systems able to accomplish new and advantageous features to treat cancer. However in many cases, the lone application of those new nanotherapeutics has proven not to be enough to achieve acceptable therapeutic efficacies. Hence, to avoid these limitations, the scientific community has been embarked on the development of single formulations capable of combining functionalities. Among all possible components, silica –either solid or mesoporous–, has become of importance as connecting and coating material for those new-generation therapeutic nanodevices. In the present review there are visited the most recent examples of fully-inorganic silica-based functional composites, paying especial attention to those with potential biomedical applicability. Additionally, there will be given some highlights about their possible biosafety issues based on their chemical composition.


Item Type:Article
Additional Information:

RESEARCH ID L-2854-2014  (Rafael Castillo Romero)
ORCID 0000-0003-1957-3098 (Rafael Castillo Romero)
RESEARCHER ID M-3378-2014 (María Vallet Regí)
ORCID 0000-0002-6104-4889 (María Vallet Regí)

Uncontrolled Keywords:Mesoporous Silica; Magnetic; Photothermal; Photodynamic; Combination therapy; Drug Delivery
Subjects:Medical sciences > Pharmacy > Inorganic chemistry
Medical sciences > Pharmacy > Pharmaceutical technology
ID Code:51567
Deposited On:04 Mar 2019 12:33
Last Modified:06 Mar 2019 09:08

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