Universidad Complutense de Madrid
E-Prints Complutense

Pharmaceuticalmicroscale and nanoscale approaches for efficient treatment of ocular diseases

Impacto

Downloads

Downloads per month over past year



Bravo-Osuna, Irene and Andrés-Guerrero, Vanessa and Pastoriza Abal, Pilar and Molina-Martínez, I.T. and Herrero-Vanrell, R. (2016) Pharmaceuticalmicroscale and nanoscale approaches for efficient treatment of ocular diseases. Drug Delivery and Translational Research, 6 (6). pp. 686-707. ISSN 2190-393X (Print) 2190-3948 (Online)

[img]
Preview
PDF
14MB

Official URL: https://link.springer.com/journal/13346



Abstract

Efficient treatment of ocular diseases can be achieved thanks to the proper use of ophthalmic formulations based on emerging pharmaceutical approaches. Among them, microtechnology and nanotechnology strategies are of great interest in the development of novel drug delivery systems to be used for ocular therapy. The location of the target site in the eye as well as the ophthalmic disease will determine the route of administration (topical, intraocular, periocular, and suprachoroidal administration) and the most adequate device.
In this review, we discuss the use of colloidal pharmaceutical systems (nanoparticles, liposomes, niosomes, dendrimers, and microemulsions), microparticles (microcapsules and microspheres), and hybrid systems (combination of different strategies) in the treatment of ophthalmic diseases. Emphasis has been placed in the therapeutic significance of each drug delivery system for clinical translation.


Item Type:Article
Uncontrolled Keywords:Microparticles, Microspheres, Nanotechnology, Nanoparticles, Ocular, Anterior segment, Posterior segment
Subjects:Medical sciences > Medicine > Ophtalmology
Medical sciences > Pharmacy
Medical sciences > Pharmacy > Pharmaceutical technology
ID Code:54792
Deposited On:01 Apr 2019 15:50
Last Modified:02 Apr 2019 10:42

Origin of downloads

Repository Staff Only: item control page