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A novel group of avian astroviruses from Neotropical passerine birds broaden the diversity and host range of Astroviridae

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Fernández-Correa, Izaskun and Truchado, Daniel A. and Gomez Lucia, Esperanza and Doménech, Ana and Pérez Tris, Javier and Schmidt-Chanasit, Jonas and Cadar, Daniel and Benítez Rico, Laura (2019) A novel group of avian astroviruses from Neotropical passerine birds broaden the diversity and host range of Astroviridae. Scientific Reports, 9 (9513). pp. 1-9. ISSN ESSN: 2045-2322

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Official URL: https://www.nature.com/articles/s41598-019-45889-3



Abstract

Metagenomics is helping to expand the known diversity of viruses, especially of those with poorly studied hosts in remote areas. The Neotropical region harbors a considerable diversity of avian species that may play a role as both host and short-distance vectors of unknown viruses. Viral metagenomics of cloacal swabs from 50 Neotropical birds collected in French Guiana revealed the presence of four complete astrovirus genomes. They constitute an early diverging novel monophyletic clade within the Avastrovirus phylogeny, representing a putative new astrovirus species (provisionally designated as Avastrovirus 5) according to the International Committee on Taxonomy of Viruses (ICTV) classifcation criteria. Their genomic organization shares some characteristics with Avastrovirus but also with Mamastrovirus. The pan-astrovirus RT-PCR analysis of the cloacal samples of 406 wild Neotropical birds showed a community-level prevalence of 4.9% (5.1% in passerines, the highest described so far in this order of birds). By screening birds of a remote region, we expanded the known host range of astroviruses to the avian families Cardinalidae, Conopophagidae, Furnariidae, Thamnophilidae, Turdidae and Tyrannidae. Our results provide important frst insights into the unexplored viral communities, the ecology, epidemiology and features of host-pathogen interactions that shape the evolution of avastroviruses in a remote Neotropical rainforest.


Item Type:Article
Uncontrolled Keywords:Avian astroviruses; Passerine birds; Astroviridae
Subjects:Medical sciences > Medicine > Parasitology
Medical sciences > Biology > Birds
ID Code:57560
Deposited On:18 Nov 2019 15:16
Last Modified:18 Nov 2019 15:35

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