Universidad Complutense de Madrid
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Genetic regulation of aflatoxin, ochratoxin A, trichothecene, and fumonisin biosynthesis: A review

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Gil-Serna, Jessica and Vázquez Estévez, Covadonga and Patiño Álvarez, Belén (2019) Genetic regulation of aflatoxin, ochratoxin A, trichothecene, and fumonisin biosynthesis: A review. International Microbiology, 23 . pp. 89-96. ISSN 1618-1905

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Official URL: https://link-springer-com.bucm.idm.oclc.org/article/10.1007/s10123-019-00084-2



Abstract

Mycotoxins are a significant food safety concern. Aflatoxins, trichothecenes, fumonisins, and ochratoxin A are considered the most important mycotoxins due to their frequent occurrence in food products and their well-known toxicity. The regulation of mycotoxin biosynthesis occurs mainly at transcriptional level, and specific regulators have been described in every biosynthetic cluster. Secondary metabolite production, including mycotoxin synthesis, is also regulated by general regulator pathways affected by light, osmotic stress and oxidative stress, among others. This review is focused on this genetic regulation of mycotoxin biosynthesis by specific genes and global regulators.


Item Type:Article
Uncontrolled Keywords:Aflatoxins, Trichothecenes, Fumonisin, Ochratoxin A, Biosynthetic cluster, Transcription factors
Subjects:Medical sciences > Biology > Biochemistry
Medical sciences > Biology > Genetics
ID Code:60554
Deposited On:18 May 2020 12:49
Last Modified:23 Sep 2020 10:35

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