Publication: Microbioma materno-infantil: aplicación al distrés posparto y alteraciones gastrointestinales y respiratorias infantiles
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2021-08-05
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Universidad Complutense de Madrid
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Abstract
La leche humana contiene numerosos nutrientes, compuestos con actividad biológica y bacterias comensales que tienen una importante influencia en la salud del niño. De todos los componentes bioactivos, la microbiota y los compuestos inmunológicos tienen una gran relevancia ya que intervienen activamente en el crecimiento y maduración de numerosos órganos y tejidos, protegen frente a agentes patógenos y contribuyen a la correcta colonización del tracto gastrointestinal. En esta colonización del intestino infantil, que se potencia espectacularmente tras el nacimiento, juega un papel especial la microbiota mamaria, que proporciona un aporte constante de bacterias al recién nacido a través de la lactancia. Por ello, cualquier factor que influya en la composición de la leche materna puede tener un reflejo directo en la salud del lactante. La composición de la leche materna ha sido objeto de numerosos estudios que han puesto de manifiesto su gran variabilidad interindividual así como su variación con diversos factores maternos y ambientales, aunque no existe información sobre la influencia que pudiera tener el distrés psicosocial posnatal materno...
Human milk contains numerous nutrients, bioactive compounds and commensal bacteria that have an important influence on infant health. Among all the bioactive components present in human milk, the microbiota and the immunological composition have great relevance since they actively determine the growth and maturation of numerous organs and tissues, protect against pathogens and contribute to the normal colonization of the gastrointestinal tract. In the gut colonization of the infant, which increases dramatically after birth, the mammary microbiota plays a special role, providing a constant supply of bacteria to the newborn through lactation. Therefore, any factor that influences the milk composition can have a direct reflection on the infant health. The composition of human milk has been the subject of several studies that have shown its great inter-individual variability as well as its variation with various maternal and environmental factors. However, there is no information on the influence that maternal postnatal psychosocial distress could have on milk composition...
Human milk contains numerous nutrients, bioactive compounds and commensal bacteria that have an important influence on infant health. Among all the bioactive components present in human milk, the microbiota and the immunological composition have great relevance since they actively determine the growth and maturation of numerous organs and tissues, protect against pathogens and contribute to the normal colonization of the gastrointestinal tract. In the gut colonization of the infant, which increases dramatically after birth, the mammary microbiota plays a special role, providing a constant supply of bacteria to the newborn through lactation. Therefore, any factor that influences the milk composition can have a direct reflection on the infant health. The composition of human milk has been the subject of several studies that have shown its great inter-individual variability as well as its variation with various maternal and environmental factors. However, there is no information on the influence that maternal postnatal psychosocial distress could have on milk composition...
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Tesis inédita de la Universidad Complutense de Madrid, Facultad de Veterinaria, Departamento de Nutrición y Ciencia de los Alimentos, leída el 23-04-2021