Publication: Monitorización anestésica avanzada durante el trasplante hepático : valor clínico de la determinación intraoperatoria de troponina
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2022-04-04
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Universidad Complutense de Madrid
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Abstract
La cirugía de trasplante hepático conlleva un alto riesgo de morbimortalidad perioperatoria, influenciada, en parte, por la aparición de eventos intraoperatorios pendientes de ser esclarecidos. La troponina es un biomarcador cardiaco fácilmente accesible que puede cuantificarse con precisión con los nuevos ensayos bioquímicos de alta sensibilidad. Los niveles altos de troponina plasmática se han asociado con una mayor mortalidad a corto plazo. Sin embargo, en el ámbito quirúrgico general, y en el del trasplante hepático en particular, la relación entre los niveles intraoperatorios de troponina y las variables clínicas y hemodinámicas, así como la supervivencia postoperatoria, es desconocida...
The procedure of liver transplantation is associated with high risk of perioperative complications including mortality influenced by intraoperative events which remain to be clarified. The troponin is an easily accessible cardiac biomarker which can be precisely quantified by new high-sensitivity assays. High levels of serum troponin are associated with higher short-term mortality. However, in the surgical context, the relationship between intraoperative troponin levels and the clinical and hemodynamic parameters, as well as post-transplant survival is unknown...
The procedure of liver transplantation is associated with high risk of perioperative complications including mortality influenced by intraoperative events which remain to be clarified. The troponin is an easily accessible cardiac biomarker which can be precisely quantified by new high-sensitivity assays. High levels of serum troponin are associated with higher short-term mortality. However, in the surgical context, the relationship between intraoperative troponin levels and the clinical and hemodynamic parameters, as well as post-transplant survival is unknown...
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Tesis inédita de la Universidad Complutense de Madrid, Facultad de Medicina, Departamento de Medicina, leída el 17-11-2021