Publication: Enfermedad celíaca en mujeres con problemas reproductivos: diagnóstico y prevalencia
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2022-04-04
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Universidad Complutense de Madrid
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Abstract
La enfermedad celíaca (EC) es una enfermedad mediada por el sistema inmunitario provocada por el gluten en individuos genéticamente susceptibles. Su prevalencia en la población general está en torno al 1%, siendo menor en la población adulta, en la que en España se ha descrito en torno al 0,27-0,32%. La EC se caracteriza por una gran variedad de manifestaciones clínicas, entre las que se incluye la infertilidad y los abortos espontáneos recurrentes (AR). No obstante, debido a la controversia generada por los datos tan heterogéneos presentes en la literatura, la infertilidad y los AR no se incluyen actualmente en los programas de cribado de la EC. La instauración de una dieta sin gluten (DSG), tratamiento actual de esta enfermedad, puede llevar a una concepción exitosa en los casos en que estos problemas reproductivos se deben a la EC, lo que dota de especial relevancia a la información que se puede obtener de nuevos estudios en relación a este tema...
Celiac disease (CD) is an immune-mediated disease caused by gluten ingestion in genetically susceptible individuals. The prevalence of CD in general population is around 1%, being lower in the adult population. In Spain, it has been described around 0.27-0.32% in adults. CD is characterized by a wide variety of clinical manifestations, including infertility and recurrent spontaneous abortions (RSA). Nevertheless, due to the controversy generated by the highly heterogeneous data present in the literature, infertility and RSA are not currently included in CD screening programs. The establishment of a gluten-free diet (GFD), current treatment of CD, can lead to a successful conception if these reproductive problems are due to undiagnosed CD, which gives special relevance to the information that can be obtained from new studies in relation to this topic...
Celiac disease (CD) is an immune-mediated disease caused by gluten ingestion in genetically susceptible individuals. The prevalence of CD in general population is around 1%, being lower in the adult population. In Spain, it has been described around 0.27-0.32% in adults. CD is characterized by a wide variety of clinical manifestations, including infertility and recurrent spontaneous abortions (RSA). Nevertheless, due to the controversy generated by the highly heterogeneous data present in the literature, infertility and RSA are not currently included in CD screening programs. The establishment of a gluten-free diet (GFD), current treatment of CD, can lead to a successful conception if these reproductive problems are due to undiagnosed CD, which gives special relevance to the information that can be obtained from new studies in relation to this topic...
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Tesis inédita de la Universidad Complutense de Madrid, Facultad de Medicina, leída el 29-11-2021