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Bloody coli: a gene cocktail in Escherichia coli O104:H4.

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Baquero, Fernando and Tobes, Raquel (2013) Bloody coli: a gene cocktail in Escherichia coli O104:H4. mBio, 4 (1). e00066-13. ISSN 2150-7511

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Official URL: http://mbio.asm.org/content/4/1/e00066-13.full.html



Abstract

A recent study published in mBio [Y. H. Grad et al., mBio 4(1):e00452-12, 2013] indicates that a rapid introgressive evolution has occurred in Escherichia coli O104:H4 by sequential acquisition of foreign genetic material involving pathogenicity traits. O104 genetic promiscuity cannot be readily explained by high population sizes. However, extensive interactions leading to cumulative assemblies of pathogenicity genes might be assured by small K-strategist populations exploiting particular intestinal niches. Next-generation sequencing technologies will be critical to detect particular "gene cocktails" as potentially pathogenic ensembles and to predict the risk of future outbreaks.


Item Type:Article
Uncontrolled Keywords:Microbiología
Subjects:Medical sciences > Pharmacy > Microbiology
ID Code:21952
Deposited On:24 Jun 2013 13:05
Last Modified:25 May 2015 08:21

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