Towards the development of smart 3D “gated scaffolds” for on-command delivery



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Mas, Núria and Arcos, Daniel and Polo, Lorena and Aznar, Elena and Sánchez Salcedo, Sandra and Sancenón, Félix and García Fontecha, Ana and Marcos Vega, M. Dolores and Baeza, Alejandro and Vallet Regí, María and Martínez-Máñez, Ramón (2014) Towards the development of smart 3D “gated scaffolds” for on-command delivery. Small, 10 (23). pp. 4859-4864. ISSN 1613-6829

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A new approach towards the design of “gated scaffolds” based on the combination of capped mesoporous silica nanoparticles (MSNs) with porous biomaterials is reported. Using this approach, a 3D gelatin-based scaffold able to selectively deliver cargo in the presence of an APase enzyme is prepared and tested. This new design opens up the possibility of developing new smart biomaterials with advanced drug-delivery features.

Item Type:Article
Palabras clave (otros idiomas):3D scaffolds
Subjects:Sciences > Chemistry > Chemistry, Inorganic
ID Code:30905
Deposited On:03 Jul 2015 11:43
Last Modified:31 Mar 2017 12:03

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