Publication: Implementación de una programa para el control del uso de antifúngicos en un hospital general universitario ("Antifungal stewardship")
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2016-07-22
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Universidad Complutense de Madrid
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Abstract
El consumo inapropiado de antifúngicos ha contribuido en años recientes al incremento global de la resistencia antifúngica y ha jugado un papel importante en los cambios epidemiológicos y en la etiología de las infecciones fúngicas. Además, el sobreuso de antifúngicos conlleva un riesgo de toxicidad asociada a los mismos y un muy significativo aumento en el gasto sanitario. Los programas de control del uso de antifúngicos consisten en intervenciones multidisciplinares, lideradas por especialistas en enfermedades infecciosas, microbiología clínica y farmacia, que establecen redes de cooperación y comunicación con los principales servicios prescriptores, con el fin de optimizar el tratamiento antifúngico y el manejo de las infecciones fúngicas invasivas. Sin embargo, la experiencia en el desarrollo de programas de optimización del uso de antifúngicos es muy limitada, pues la mayoría de los esfuerzos se han centrado en el control de los antibacterianos...
The frequency of use of systemic antifungal agents has increased significantly in most tertiary care centers. The inappropriate use of antifungals in recent years has played an important role in the epidemiological changes on fungal etiology, leading to an increase in fungal resistance and emergent fungi. Moreover, this antifungal overuse increases the potential for drug related toxicity and implies an “extra” cost for the health system. Antifungal stewardship programs are multidisciplinary interventions lead by infectious disease specialists, clinical microbiologists and pharmaceutics networking with other specialists from the main prescribing departments, with the common objective of optimize the management of fungal infections and antifungal use. However, antifungal stewardship has received very little attention...
The frequency of use of systemic antifungal agents has increased significantly in most tertiary care centers. The inappropriate use of antifungals in recent years has played an important role in the epidemiological changes on fungal etiology, leading to an increase in fungal resistance and emergent fungi. Moreover, this antifungal overuse increases the potential for drug related toxicity and implies an “extra” cost for the health system. Antifungal stewardship programs are multidisciplinary interventions lead by infectious disease specialists, clinical microbiologists and pharmaceutics networking with other specialists from the main prescribing departments, with the common objective of optimize the management of fungal infections and antifungal use. However, antifungal stewardship has received very little attention...
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Tesis inédita de la Universidad Complutense de Madrid, Facultad de Medicina, leída el 30/11/2015. Tesis formato europeo (compendio de artículos)