Evidence of Leishmania infantum infection in rabbits (Oryctolagus cuniculus) in a natural area in Madrid, Spain



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García Benzaquén, Nerea and Moreno, Inmaculada and Alvarez, Julio and Cruz Conty, María Luisa and Navarro Gómez, Alejandro and Pérez Sancho, Marta and García Seco, Teresa and Rodríguez Bertos, Antonio and Conty, María Luisa and Toraño, Alfredo and Prieto, Antonio and Domínguez Rodríguez, Lucas and Domínguez, Mercedes (2014) Evidence of Leishmania infantum infection in rabbits (Oryctolagus cuniculus) in a natural area in Madrid, Spain. BioMed Research International, 2014 . pp. 1-5. ISSN 2314-6133

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Official URL: http://dx.doi.org/10.1155/2014/318254


Leishmaniasis is one of most important neglected zoonosis and remains endemic in at least 88 developing countries in the world. In addition, anthropogenic environmental changes in urban areas are leading to its emergency world-wide. Zoonotic leishmaniasis control might only be achieved by an integrated approach targeting both the human host and the animal reservoirs, which in certain sylvatic cycles are yet to be identified. Recently, hares have been pointed out as competent reservoirs of Leishmania infantum in Spain, but the role of other lagomorphs has not been clarified. Here, 69 rabbits (Oryctolagus cuniculus) from a natural area in Madrid in which a high density was present were analyzed using indirect (immunofluorescence antibody test, IFAT) and direct (PCR, culture) techniques. Fifty-seven (82.6%) of the animals were positive to at least one technique, with IFAT yielding the highest proportion of positive samples. L. infantum was isolated in 13% animals demonstrating the occurrence of infection in this setting. Our results suggest that rabbits could play a role of competent reservoir of L. infantum and demonstrate that the prevalence of infection is high in the analyzed area.

Item Type:Article
Subjects:Medical sciences > Veterinary
ID Code:39705
Deposited On:20 Dec 2016 11:22
Last Modified:20 Dec 2016 11:22

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