Corneal densitometry after photorefractive keratectomy, laser- assisted in situ keratomileusis, and small-incision lenticule extraction



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Poyales Galán, Francisco and Garzón Jiménez, Nuria and Mendicute, Javier and Illarramendi, Igor and Caro, Pedro and Jáñez, Oscar and Argüeso Díaz-Trechuelo, Francisco and López, Alfredo (2017) Corneal densitometry after photorefractive keratectomy, laser- assisted in situ keratomileusis, and small-incision lenticule extraction. Eye . ISSN 0950-222X (In Press)

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Purpose: The aim of this study was to gain greater insight into the corneal densitometry changes occurring as a result of refractive surgery and to compare these changes across three widely used surgical techniques, namely, photorefractive keratectomy (PRK), laser-assisted in situ keratomileusis with a femtosecond laser (LASIK-FS), or ReLEx small-incision lenticule extraction (ReLEx SMILE).
Patients and methods: Three hundred and thirty-six patients (184 male and 152 female patients) participated in this study. They were split into three groups according to the refractive surgery technique they had undergone: LASIK-FS (74 patients), PRK (153 patients), and ReLEx SMILE (109 patients). All participants underwent an exhaustive eye examination both before and after surgery. Pre- and postoperative corneal densitometry was measured using an Oculus Pentacam system.
Results: The mean postoperative total corneal densitometry values were 16.53 ± 1.94 for the LASIK- FS group, 15.53 ± 1.65 for PRK, and 16.10 ± 1.54 for ReLEx SMILE. When corneal densitometry was analyzed for specific corneal areas, the values corresponding to the 0–2, 2–6, and 6–10 mm annuli were similar across the three surgical techniques. The only region in which differences were found was the peripheral area (Po0.05), but these variations across techniques were not statistically significant.
Conclusions: Corneal densitometry can be used as an objective metric to assess corneal response to refractive surgery, and to monitor patients over time. Corneal densitometry was not negatively affected by any of the refractive surgical procedures under evaluation.

Item Type:Article
Additional Information:

Received: 29 September 2016 ; Accepted in revised form: 27 April 2017

Uncontrolled Keywords:Corneal densitometry ; Keratectomy ; Keratomileusis ; Refractive surgery ; PRK ; Femtomsecond laser ; ReLEx SMILE
Subjects:Medical sciences > Medicine > Surgery
Medical sciences > Medicine > Ophtalmology
Medical sciences > Optics > Optometry
ID Code:43018
Deposited On:02 Jun 2017 11:32
Last Modified:27 Sep 2017 23:01

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