Publication: Self-immolative chemistry in nanomedicine
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Publication Date
2017-12-23
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Abstract
Self-immolative chemistry is based on the cascade of disassembling reactions triggered by the adequate stimulation and leading to the sequential release of the smaller constituent elements. This review will focus on the possibilities that this type of chemistry offers to nanomedicine research, which is an area where the stimuli responsive behavior is always targeted. There are some examples on the use of self-immolative chemistry for prodrugs or nanoparticles for drug delivery, but there is still an exciting land of opportunities waiting to be explored. This review aims at revising what has been done so far, but, most importantly, it aims at inspiring new research of self-immolative chemistry on nanomedicine.
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RESEARCHER ID S-2443-2016 (Miguel Gisbert Garzarán)
ORCID 0000-0001-9815-0354 (Miguel Gisbert Garzarán)
RESEARCHER ID K-3719-2014 (Miguel Manzano García)
ORCID 0000-0001-6238-6111 (Miguel Manzano García)
RESEARCHER ID M-3378-2014 (María Vallet Regí)
ORCID 0000-0002-6104-4889 (María Vallet Regí)