Changes in corneal biomechanical properties after 24 hours of continuous intraocular pressure monitoring using a contact lens sensor



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Morales Fernández, Laura and García Bella, Javier and Martínez de la Casa, Jose Maria and Sánchez Jean, Rubén and Sáenz Francés, Federico and Arriola Villalobos, Pedro and Perucho González, Lucía and Santos Bueso, Enrique and García Feijoo, Julián (2017) Changes in corneal biomechanical properties after 24 hours of continuous intraocular pressure monitoring using a contact lens sensor. Canadian Journal of Ophthalmology . 5 p.. ISSN 1715-3360 (In Press)

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Objective: This study was designed to assess changes in corneal topography and biomechanics after intraocular pressure (IOP) monitoring using the Triggerfish contact lens sensor (CLS).
Methods: For this prospective study, 30 eyes of 30 subjects: 14 healthy subjects (G1) and 6 glaucoma patients (G2), were recruited for 24 hours of continuous IOP monitoring using the CLS. The following measurements were taken before CLS fitting and after lens removal: maximum keratometry (Kmax), mean keratometry (MK), and corneal astigmatism (Cyl) measured through Pentacam corneal topography, and the corneal biomechanical variables corneal hysteresis (CH) and corneal resistance factor (CRF) measured with the Ocular Response Analyzer (ORA).
Results: Pentacam data revealed significant changes after CLS removal in Kmax (+3.14 ± 2.46 D, p = 0.002), MK (+0.52 ± 0.63 D, p = 0.02), and Cyl (+0.48 ± 0.53 D, p = 0.019) in G1; and Kmax (+1.38 ± 1.43 D, p = 0.002) in G2. The changes observed were more pronounced in G1 than in G2 but differences were not significant. The ORA results indicated higher CH (11.35 ± 2.42 vs 8.17 ± 2.09) and CRF (10.3 ± 2.03 vs 9.1 ± 1.81) before lens fitting in G1 than G2, while no significant changes were produced after CLS removal in either group.
Conclusions: The use of CLS for IOP monitoring over 24 hours caused topographic changes in both healthy subjects and glaucoma patients. No changes were produced in corneal biomechanics.

Item Type:Article
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Received 17 April 2017, Revised 5 October 2017, Accepted 10 October 2017, Available online 18 December 2017.

Uncontrolled Keywords:Cornea; Intraocular pressure; Contact lens sensor; Corneal biomechanical properties; Glaucoma; Corneal topography; Pentacam;
Subjects:Medical sciences > Medicine > Ophtalmology
Medical sciences > Optics > Contact lenses
Medical sciences > Optics > Imaging systems
ID Code:46071
Deposited On:22 Jan 2018 13:34
Last Modified:18 Dec 2018 00:01

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