Publication: Valoración de la discromatopsia adquirida mediante nueva aplicación informática en pacientes con neuropatías ópticas desmielinizantes
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2018-03-21
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Universidad Complutense de Madrid
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Abstract
Las neuritis ópticas son una de las manifestaciones más frecuentes e invalidantes de la esclerosis múltiple. Se ve afectada entre otras funciones visuales la percepción del color, produciendo una discromatopsia adquirida. La mayoría de pruebas existentes para evaluar la discromatopsias fueron diseñadas para los casos congénitos (pruebas de Farnsworth e Ishihara). Así mismo, las pruebas empleadas para el estudio de las neuritis ópticas se basan en otras funciones visuales como agudeza visual y sensibilidad periférica (campimetría automatizada), pero no existen pruebas validadas para estudiar la discromatopsia adquirida en neuritis ópticas. Su evaluación sistemática puede aportar información sobre evolución, respuesta a tratamientos y pronóstico, ya que se ha comprobado que es una de las funciones visuales más alteradas a corto y largo plazo y más específica para evaluar la función del nervio óptico. 2 Justificación: La afectación visual en pacientes con neuritis óptica desmielinizante precisa de una prueba validada, de rápida administración, asequible y con una validez adecuada para evaluar la discromatopsia adquirida. Dicha prueba no existe hasta la fecha y puede ayudar a conocer el grado de discapacidad, pronóstico y planificar la eficacia de los tratamientos administrados...
Optic neuritis is one of the most common and invalidating manifestations of multiple sclerosis. The perception of color is affected among other visual functions, producing an acquired dyschromatopsia. Most existing tests to assess discromatopsias were designed for congenital cases (Farnsworth and Ishihara tests). Moreover, the tests used for the study of optic neuritis are based on other visual functions such as visual acuity and peripheral sensitivity (automated campimetry), but there are no validated tests to study the mentioned acquired dyschromatopsia in optic neuritis. Relevant information about clinical evolution, response to treatment and prognosis can be provide by systematic evaluation of the dyschromatopsia, as it has been proven to be one of the most altered visual functions in the short-term and longterm. Also, is one of the more specific visual function to evaluate the optic nerve. 2 Justification: Visual impairment in patients with demyelinating optic neuritis requires a validated, readily available, and validated test to assess acquired dyschromatopsia. This test does not exist to date and can help to know the degree of disability, prognosis and plan the effectiveness of the treatments administered. 3 Hypothesis: Acquired dyschromatopsia after the first episode of demyelinating optic neuritis is detectable and quantifiable by ADET test after the acute phase...
Optic neuritis is one of the most common and invalidating manifestations of multiple sclerosis. The perception of color is affected among other visual functions, producing an acquired dyschromatopsia. Most existing tests to assess discromatopsias were designed for congenital cases (Farnsworth and Ishihara tests). Moreover, the tests used for the study of optic neuritis are based on other visual functions such as visual acuity and peripheral sensitivity (automated campimetry), but there are no validated tests to study the mentioned acquired dyschromatopsia in optic neuritis. Relevant information about clinical evolution, response to treatment and prognosis can be provide by systematic evaluation of the dyschromatopsia, as it has been proven to be one of the most altered visual functions in the short-term and longterm. Also, is one of the more specific visual function to evaluate the optic nerve. 2 Justification: Visual impairment in patients with demyelinating optic neuritis requires a validated, readily available, and validated test to assess acquired dyschromatopsia. This test does not exist to date and can help to know the degree of disability, prognosis and plan the effectiveness of the treatments administered. 3 Hypothesis: Acquired dyschromatopsia after the first episode of demyelinating optic neuritis is detectable and quantifiable by ADET test after the acute phase...
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Tesis inédita de la Universidad Complutense de Madrid, Facultad de Medicina, Departamento de Oftalmología y Otorrinolaringología, leída el 18-07-2017