Publication: Recursos tecnológicos en comprimidos de liberación sostenida.
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2016-01
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Abstract
Los sistemas matriciales y los sistemas osmóticos son unas de las formas farmacéuticas orales de liberación sostenida más empleadas actualmente en la industria farmacéutica. Su desarrollo ha permitido mejorar enormemente el tratamiento de gran variedad de patologías debido a su capacidad para proporcionar niveles plasmáticos de fármaco casi constantes, disminuyendo la aparición de efectos adversos y mejorando el cumplimiento terapéutico por parte del paciente. Algunas enfermedades en las que se emplean este tipo de sistemas son la diabetes, al comercializarse medicamentos como el Diamicron MR® basado en un sistema matricial, o la hiperplasia benigna de próstata con el Carduran Neo®, el cual está basado en un sistema osmótico.
Matrix and osmotic systems are one of the most used controlled drug delivery systems in the industry nowadays. Its development has allowed the improvement in treatments of a great variety of illnesses due to their capacity to maintain almost sustained plasma drug levels, thus decreasing the risk of side-effects and improving the medication adherence from the patients’ point of view. Some of the diseases that are already being treated by these type of systems are diabetes, with the commercialization of drugs such as matrixbased Diamicron MR®, or benign prostatic hyperplasia, with the osmotic-based Carduran Neo®.
Matrix and osmotic systems are one of the most used controlled drug delivery systems in the industry nowadays. Its development has allowed the improvement in treatments of a great variety of illnesses due to their capacity to maintain almost sustained plasma drug levels, thus decreasing the risk of side-effects and improving the medication adherence from the patients’ point of view. Some of the diseases that are already being treated by these type of systems are diabetes, with the commercialization of drugs such as matrixbased Diamicron MR®, or benign prostatic hyperplasia, with the osmotic-based Carduran Neo®.