Publication: Identificación, descripción y análisis crítico de ensayos clínicos controlados publicados en revistas odontológicas de habla hispana
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2018-10-23
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Universidad Complutense de Madrid
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Abstract
Los ensayos clínicos se utilizan para evaluar la eficacia de las intervenciones clínicas tanto en medicina como en odontología. Éstos se establecen como el diseño primario óptimo y se publican cada vez con mayor frecuencia dentro de las ciencias biomédicas, incluida la odontología. Diversos tipos de sesgos pueden comprometer sus resultados y afectar su validez interna. Los ensayos clínicos aleatorizados bien diseñados y correctamente ejecutados proporcionan la mejor evidencia sobre el efecto de las intervenciones sanitarias, pero una metodología inadecuada puede resultar en estimaciones exageradas de este efecto. OBJETIVO: El objetivo del presente trabajo es identificar, describir y evaluar la calidad metodológica de los ensayos clínicos controlados que se publican en revistas de odontología de habla hispana. Además se ha tratado de establecer si existe una relación entre la calidad de los ensayos clínicos identificados y la especialidad, el país o el periodo de tiempo en el que fueron publicados...
Clinical trials are used to evaluate the effectiveness of clinical interventions in both Medicine and Dentistry. These are established as the optimal primary design and are increasingly being published within the Biomedical Sciences, including Dentistry. Controlled clinical trials are considered the best approach to analyze the effects (benefits or harms) of a therapeutic intervention, drug, device or technique in human beings. Different types of bias can compromise results and affect their internal validity. Well-designed and correctly executed randomized clinical trials provide the best evidence of the effect of health interventions, but inadequate methodology may result in exaggerated estimates of this effect. OBJECTIVE: The aim of the present study is to identify, describe and evaluate the methodological quality of controlled clinical trials published in Spanish language dental journals. In addition, an attempt has been made to establish whether there is a relationship between the quality of the clinical trials identified and the country, dental specialty or period of time in which they were published...
Clinical trials are used to evaluate the effectiveness of clinical interventions in both Medicine and Dentistry. These are established as the optimal primary design and are increasingly being published within the Biomedical Sciences, including Dentistry. Controlled clinical trials are considered the best approach to analyze the effects (benefits or harms) of a therapeutic intervention, drug, device or technique in human beings. Different types of bias can compromise results and affect their internal validity. Well-designed and correctly executed randomized clinical trials provide the best evidence of the effect of health interventions, but inadequate methodology may result in exaggerated estimates of this effect. OBJECTIVE: The aim of the present study is to identify, describe and evaluate the methodological quality of controlled clinical trials published in Spanish language dental journals. In addition, an attempt has been made to establish whether there is a relationship between the quality of the clinical trials identified and the country, dental specialty or period of time in which they were published...
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Tesis inédita de la Universidad Complutense de Madrid de la Facultad de Odontología del Departamento de Estomatología IV (Profilaxis, Odontopediatría y Ortodoncia), leída el 30 de Junio de 2017.