Publication: Nuevas estrategias en el tratamiento de la obesidad y sus complicaciones. Efecto de la fucoxantina
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2016-06
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Abstract
La obesidad es un trastorno prevenible en la mayoría de los casos y consiste en la acumulación excesiva de tejido adiposo en el organismo. Esta patología supone un factor de riesgo para padecer otras enfermedades. Debido al cambio en el estilo de vida y la alimentación, la prevalencia de la obesidad ha aumentado y esto ha hecho que surja la necesidad de encontrar una alternativa terapéutica eficaz para poder tratarla así como las complicaciones derivadas de esta enfermedad. En la búsqueda de un tratamiento eficaz, se ha encontrado una molécula, la fucoxantina, que ha demostrado ser efectiva para esta enfermedad, así como para las complicaciones y por ello está siendo estudiada. En estos estudios se ha demostrado que tiene un potencial uso para tratar la obesidad al favorecer el gasto energético mediante la disipación de calor en el tejido adiposo debido a la inducción de la UCP1 (proteína desacopladora) así como en las complicaciones en el tratamiento de las hiperlipidemias, del cáncer, efecto antiinflamatorio, efecto contra el estrés celular causado por los radicales libres así como para tratar el hígado graso.
Obesity is a disorder preventable in most cases consisting of excessive accumulation of adipose tissue. This condition is a risk factor for developing other diseases. Due to the change in lifestyle and diet, the prevalence of obesity has increased and this has made the need to find an effective compound to treat it and its complications with a therapeutic alternative. In the search for effective treatment, it has been found a molecule, fucoxanthin, which has proven effective for this disease, as well as its complications and therefore is being studied. In these studies it has been shown to have potential use to treat obesity by promoting energy expenditure by heat dissipation in adipose tissue due to induction of ucp1 (uncoupling protein) as well as complications in the treatment of hyperlipidemia, cancer, antiinflammatory effect, effect against cellular stress caused by free radicals and to treat fatty liver.
Obesity is a disorder preventable in most cases consisting of excessive accumulation of adipose tissue. This condition is a risk factor for developing other diseases. Due to the change in lifestyle and diet, the prevalence of obesity has increased and this has made the need to find an effective compound to treat it and its complications with a therapeutic alternative. In the search for effective treatment, it has been found a molecule, fucoxanthin, which has proven effective for this disease, as well as its complications and therefore is being studied. In these studies it has been shown to have potential use to treat obesity by promoting energy expenditure by heat dissipation in adipose tissue due to induction of ucp1 (uncoupling protein) as well as complications in the treatment of hyperlipidemia, cancer, antiinflammatory effect, effect against cellular stress caused by free radicals and to treat fatty liver.