Publication: Efectividad de pastas dentales a base de calcio, fosfato y flúor en la remineralización de lesiones iniciales de caries
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2019-04-24
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Universidad Complutense de Madrid
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Abstract
Las lesiones de manchas blancas (WSL) representan el primer signo de caries dental producto del desequilibrio de la desmineralización (des) - remineralización (re). Los agentes fluorados son comúnmente usados como tratamiento de WSL, sin embargo, se han introducido otras terapias con tecnologías de nanopartículas. Entre los productos que usan complejos de calcio [Ca], fósforo [P] y flúor [F] encontramos Remin Pro®, hidroxiapatita fluorada (HA+F); Mi Paste PlusTM, fosfopéptido de caseína - fosfato de calcio amorfo fluorado (CPP-ACPF); Clinpro™ Tooth Crème, fosfato tricálcico fluorado (f-TCP) y Sensodyne® Repair&Protect, fosfosilicato de calcio y sodio fluorado (CSPS+F). Se cree que esta combinación de minerales es capaz de detener lesiones activas por medio de la acción compleja de iones. La hipótesis de estudio fue que las pastas dentales basadas en calcio-fosfato-flúor son efectivas para el tratamiento de lesiones iniciales de caries.Objetivo: El objetivo de esta serie de trabajos fue evaluar la efectividad de cuatro pastas dentales a base de calcio-fosfato-flúor en la remineralización de lesiones iniciales de caries observadas en la microdureza y morfología (Estudio 1), el perfil mineral-ultraestructural (Estudio 2), la regresión y descalcificación (Estudio 3)...
White spot lesions (WSL) represent the first sign of dental caries due to an imbalance of the demineralization process (des) - remineralization (re). Fluorinated agents are commonly used for the treatment of WSL, however, there are also therapies that have introduced new nanoparticle technologies. Among the products that use complexes of calcium [Ca], phosphate [P] and fluorine [F] we find Remin Pro®), which is hydroxyapatite-fluoride (HA+F); Mi Paste PlusTM, which contains casein phosphopeptide-amorphous calcium phosphate fluoride (CPP-ACPF); Clinpro™ Tooth Crème, fluoridated tricalcium phosphate (f-TCP) and Sensodyne® Repair&Protect, calcium sodium phosphosilicate fluoride (CSPS + F). It is believed that this combination of minerals may be able to stop active lesions of caries by means of the complex action of its ions for the mineral gain. The study hypothesis was that toothpastes based on calcium-phosphate-fluoride are effective for the treatment of initial lesions of caries...
White spot lesions (WSL) represent the first sign of dental caries due to an imbalance of the demineralization process (des) - remineralization (re). Fluorinated agents are commonly used for the treatment of WSL, however, there are also therapies that have introduced new nanoparticle technologies. Among the products that use complexes of calcium [Ca], phosphate [P] and fluorine [F] we find Remin Pro®), which is hydroxyapatite-fluoride (HA+F); Mi Paste PlusTM, which contains casein phosphopeptide-amorphous calcium phosphate fluoride (CPP-ACPF); Clinpro™ Tooth Crème, fluoridated tricalcium phosphate (f-TCP) and Sensodyne® Repair&Protect, calcium sodium phosphosilicate fluoride (CSPS + F). It is believed that this combination of minerals may be able to stop active lesions of caries by means of the complex action of its ions for the mineral gain. The study hypothesis was that toothpastes based on calcium-phosphate-fluoride are effective for the treatment of initial lesions of caries...
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Tesis inédita de la Universidad Complutense de Madrid de la Facultad de Odontología. Departamento de Especialidades Clínicas Odontológicas, leída el 14-12-2018.