Comparison of the impact of nesofilcon A hydrogel contact lens on the ocular surface and the comfort of presbyopic and non-presbyopic wearers



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Lorente Velázquez, Amalia and García Montero, María and Gómez Sanz, Fernando Javier and Rico del Viejo, Laura and Hernández Verdejo, José Luis and Madrid Costa, David (2019) Comparison of the impact of nesofilcon A hydrogel contact lens on the ocular surface and the comfort of presbyopic and non-presbyopic wearers. International journal of ophthalmology, 12 (4). pp. 640-646. ISSN 2222-3959

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AIM: To assess and compare the impact of a daily disposable contact lens (CL) with high water content on the ocular surface and comfort of the presbyopic and non-presbyopic population after one day of use.
METHODS: Totally 20 presbyopes and 30 non-presbyopes non-contact wearers were fitted with nesofilcon A CLs. CL thickness was measured to assess material stability during daily wear, and ocular surface parameters were also assessed. Optical quality was analyzed for all cases. In addition, CL comfort was rated.
RESULTS: No significant differences were found in CL thickness, tear film osmolarity, average tear break-up time, bulbar redness, central corneal thickness, corneal volume, root-mean-square of higher-order aberrations (RMS of HOAs) and vertical and horizontal coma, either as a function of the group or time of use. A significant decrease in tear meniscus height and first break-up of the tear film was found in the presbyopic group (P=0.038; P=0.007 respectively). A decrease in spherical aberration coefficient was found after CL insertion (P=0.031 monofocal CL; P=0.023 low addition multifocal CL; P=0.016 high addition multifocal CL). Multifocal CL were thicker than monofocal CL (P=0.045). Comparison between groups showed more discomfort in presbyopes than non-presbyopes (P=0.003).
CONCLUSION: This study evidence that the behavior of the daily disposable CL with high water content seems to be stable during the day of use. Ocular parameters measured during wear show that CL behavior is the same for presbyopes and non-presbyopes, being more uncomfortable for presbyopes.

Item Type:Article
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Received:July 24, 2018 Revised:December 13, 2018

Uncontrolled Keywords:Nesofilcon A hydrogel material; Ocular surface parameters; Presbyopia; Multifocal daily contact lenses
Subjects:Medical sciences > Optics > Contact lenses
Medical sciences > Optics > Optometry
Medical sciences > Optics > Physiological optics
ID Code:55125
Deposited On:06 May 2019 10:50
Last Modified:06 May 2019 10:50

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