Publication: Conectividad funcional y procesos inhibitorios en las recaídas en el consumo de alcohol
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2019-05-17
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Universidad Complutense de Madrid
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Abstract
El consumo crónico de alcohol supone ciertas disfunciones cognitivas, aunque los déficits ejecutivos son centrales y están relacionados con el curso de la enfermedad. Específicamente, el control inhibitorio, cognitivo y conductual o la capacidad de toma de decisiones resultan clave en el éxito terapéutico y mantenimiento de la abstinencia. Estas alteraciones se han asociado a deficiencias en el funcionamiento neural tanto en estados interoceptivos de reposo, como durante procesos cognitivos asociados a la inhibición, el control atencional o la toma de decisiones. Por lo tanto, se plantean los siguientes objetivos en este trabajo: 1. Evaluar en contextos relacionados con la sustancia la toma de decisión léxica y la inhibición motora. 2. Evaluar la actividad psicofisiológica subyacente a procesos léxicos e inhibitorios y en presencia de estímulos asociados a la sustancia. 3. Evaluar la actividad cerebral en reposo en términos de oscilaciones y conectividad funcional...
Chronic consumption of alcohol is characterized by several cognitive deficits, although executive dysfunctions are fundamentally related to the course of the disease. Specifically, the cognitive and motor inhibitory control, and the decision making capacity have shown a key role for treatment positive outcomes and abstinence maintenance. These alterations have been associated to neural functioning deficiencies in resting-state, as well as during cognitive processes related to inhibition, attentional control or decision making. Thus, the following aims are presented for this work:1. To assess the inhibitory control and lexical decision making in substance-related contexts.2. To evaluate the psychophysiological activity related to lexical and inhibitory processes and in presence of substance-related stimuli.3. To evaluate the resting-state brain activity in terms of oscillations and functional connectivity...
Chronic consumption of alcohol is characterized by several cognitive deficits, although executive dysfunctions are fundamentally related to the course of the disease. Specifically, the cognitive and motor inhibitory control, and the decision making capacity have shown a key role for treatment positive outcomes and abstinence maintenance. These alterations have been associated to neural functioning deficiencies in resting-state, as well as during cognitive processes related to inhibition, attentional control or decision making. Thus, the following aims are presented for this work:1. To assess the inhibitory control and lexical decision making in substance-related contexts.2. To evaluate the psychophysiological activity related to lexical and inhibitory processes and in presence of substance-related stimuli.3. To evaluate the resting-state brain activity in terms of oscillations and functional connectivity...
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Tesis de la Universidad Complutense de Madrid, Facultad de Psicología, leída el 13-12-2018