Publication: Papel patógeno de blastocystis spp
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2017-06
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Abstract
Blastocystis spp es un protozoo de amplia distribución a nivel mundial, que coloniza el tracto intestinal de múltiples organismos entre ellos el ser humano. Se localiza tanto en individuos sintomáticos como asintomáticos, pero aún se desconoce si tiene un papel patógeno o comensal. La virulencia de este protozoo no solo se asocia con el subtipo, sino también con la forma ameboide, la secreción de proteasas y la coinfección con otros patógenos. Blastocystis spp es capaz de evadir el sistema inmune, promover su supervivencia y causar daño en el hospedador mediante distintos mecanismos. Por consiguiente, parece estar implicado en el desarrollo de urticaria crónica, “Blastocystosis” y síndrome del intestino irritable (SII), además de potenciar procesos cancerígenos.
Blastocystis spp is a widely distribution worldwide protozoan, which colonizes the tracto intestinal of multiple organisms including humans. It is located in symptomatic and asymptomatic individuals, but it is still unknown if it has a pathogenic or commensal rol. The virulence of this protozoan is not only associated with the subtype, but also with the amoeboid form, the secretion of proteases and the co-infection with other pathogens. It is able to avoid the immune system, promote its survival and cause damage to the host through different mechanisms. Therefore, it seems to be involved in development of diseases such as chronic urticaria, "Blastocystosis" and irritable bowel syndrome (IBS), in addition to promote carcinogenic processes.
Blastocystis spp is a widely distribution worldwide protozoan, which colonizes the tracto intestinal of multiple organisms including humans. It is located in symptomatic and asymptomatic individuals, but it is still unknown if it has a pathogenic or commensal rol. The virulence of this protozoan is not only associated with the subtype, but also with the amoeboid form, the secretion of proteases and the co-infection with other pathogens. It is able to avoid the immune system, promote its survival and cause damage to the host through different mechanisms. Therefore, it seems to be involved in development of diseases such as chronic urticaria, "Blastocystosis" and irritable bowel syndrome (IBS), in addition to promote carcinogenic processes.