Publication: Phosphorylation of FOXO Proteins as a Key Mechanism to Regulate Their Activity
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Publication Date
2019
Authors
Orea-Soufi, Alba
Dávila, David
Lorente Pérez, María del Mar
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Publisher
Springer
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Abstract
Phosphorylation of FOXO transcription factors is one of the key mechanisms involved in the regulation of the activity, nucleo-cytosolic shuttling, and stability of this family of proteins. Here, we describe several experimental approaches allowing analysis of changes in the phosphorylation of these proteins upon exposure to different stimuli.